Targeting B-Cell Receptor Signaling for Anticancer Therapy: The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Induces Impressive Responses in B-Cell Malignancies

被引：96
|
作者：
Wiestner, Adrian [1 ]
机构：
[1] NHLBI, NIH, Bethesda, MD 20892 USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2013年 / 31卷 / 01期
关键词：
CHRONIC LYMPHOCYTIC-LEUKEMIA; ANTIGEN; LYMPHOMA; PCI-32765; ACTIVATION; REGRESSION; INDICATE; SURVIVAL; BIOLOGY; SETS;
D O I：
10.1200/JCO.2012.44.4281
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：128 / 130
页数：3
相关论文
共 50 条
  • [11] Targeting B-cell signaling pathways: a central role for Bruton's tyrosine kinase
    de Lartigue, Jane
    JOURNAL OF COMMUNITY AND SUPPORTIVE ONCOLOGY, 2014, 12 (06): : 222 - 227
  • [12] A Small Molecule Inhibitor of Bruton's Tyrosine Kinase Involved in B-Cell Signaling
    Ratzon, Einav
    Bloch, Itai
    Nicola, Meshel
    Cohen, Elad
    Ruimi, Nili
    Dotan, Nesly
    Landau, Meytal
    Gal, Maayan
    ACS OMEGA, 2017, 2 (08): : 4398 - 4410
  • [13] Current Status of Bruton's Tyrosine Kinase Inhibitor Development and Use in B-Cell Malignancies
    Aw, Andrew
    Brown, Jennifer R.
    DRUGS & AGING, 2017, 34 (07) : 509 - 527
  • [14] Current Status of Bruton’s Tyrosine Kinase Inhibitor Development and Use in B-Cell Malignancies
    Andrew Aw
    Jennifer R. Brown
    Drugs & Aging, 2017, 34 : 509 - 527
  • [15] Inhibiting Bruton's Tyrosine Kinase in CLL and Other B-Cell Malignancies
    Lucas, Fabienne
    Woyach, Jennifer A.
    TARGETED ONCOLOGY, 2019, 14 (02) : 125 - 138
  • [16] Inhibiting Bruton’s Tyrosine Kinase in CLL and Other B-Cell Malignancies
    Fabienne Lucas
    Jennifer A. Woyach
    Targeted Oncology, 2019, 14 : 125 - 138
  • [17] Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B-cell receptor signaling in mice
    Rip, Jasper
    de Bruijn, Marjolein J. W.
    Neys, Stefan F. H.
    Singh, Simar Pal
    Willar, Jonas
    van Hulst, Jennifer A. C.
    Hendriks, Rudi W.
    Corneth, Odilia B. J.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2021, 51 (09) : 2251 - 2265
  • [18] Targeting Bruton's tyrosine kinase in B cell malignancies
    Rudi W. Hendriks
    Saravanan Yuvaraj
    Laurens P. Kil
    Nature Reviews Cancer, 2014, 14 : 219 - 232
  • [19] Targeting Bruton's tyrosine kinase in B cell malignancies
    Hendriks, Rudi W.
    Yuvaraj, Saravanan
    Kil, Laurens P.
    NATURE REVIEWS CANCER, 2014, 14 (04) : 219 - 232
  • [20] Targeting of B-cell receptor signalling in B-cell malignancies
    Jerkeman, M.
    Hallek, M.
    Dreyling, M.
    Thieblemont, C.
    Kimby, E.
    Staudt, L.
    JOURNAL OF INTERNAL MEDICINE, 2017, 282 (05) : 415 - 428
12345