The art and design of genetic screens:: Arabidopsis thaliana

被引：151

作者：

Page, DR ^{[1
]}

Grossniklaus, L ^{[1
]}

机构：

[1] Univ Zurich, Inst Plant Biol, CH-8008 Zurich, Switzerland

来源：

NATURE REVIEWS GENETICS | 2002年 / 3卷 / 02期

关键词：

D O I：

10.1038/nrg730

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Molecular genetic studies rely on well-characterized organisms that can be easily manipulated. Arabidopsis thaliana - the model system of choice for plant biologists - allows efficient analysis of plant function, combining classical genetics with molecular biology. Although the complete sequence of the Arabidopsis genome allows the rapid discovery of the molecular basis of a characterized mutant, functional characterization of the Arabidopsis genome depends on well-designed forward genetic screens, which remain a powerful strategy to identify genes that are involved in many aspects of the plant life cycle.

引用

页码：124 / 136

页数：13

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