Ni-Catalyzed Denitrogenative Cross-Coupling of Benzotriazinones and Cyclopropanols: An Easy Access to Functionalized β-Aryl Ketones

被引：54
作者：
Li, Jincan [1 ]
Zheng, Yan [1 ]
Huang, Mingxian [1 ]
Li, Wanfang [1 ]
机构：
[1] Univ Shanghai Sci & Technol, Coll Sci, Shanghai 200093, Peoples R China
来源：
ORGANIC LETTERS | 2020年 / 22卷 / 13期
基金：
中国国家自然科学基金;
关键词：
ALKYNE INSERTION; BOND-CLEAVAGE; ANNULATION; TRIAZENES; 1,2,3-BENZOTRIAZIN-4(3H)-ONES; ARYLATION;
D O I：
10.1021/acs.orglett.0c01579
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel Ni-catalyzed denitrogenative cross-coupling between benzotriazinones and cyclopropanols is reported herein. This neoteric reactivity allows for the convenient synthesis of beta-(o-amido)aryl ketones from readily available starting materials with good yields (up to 93%) and general substrate scope.
引用
收藏
页码：5020 / 5024
页数：5
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