Structural and spectral assignments of six anthraquinone derivatives from the mangrove fungus (ZSUH-36)

被引：30

作者：

Shao, Changlun ^{[1
,2
]}

Wang, Changyun ^{[2
]}

Wei, Meiyan ^{[2
,3
]}

Li, Shangde ^{[3
]}

She, Zhigang ^{[1
]}

Gu, Yucheng ^{[4
]}

Lin, Yongcheng ^{[1
]}

机构：

[1] Sun Yat Sen Zhongshan Univ, Sch Chem & Chem Engn, Guangzhou 510275, Guangdong, Peoples R China

[2] Ocean Univ China, Sch Med & Pharm, Qingdao 266003, Peoples R China

[3] Guang Dong Med Coll, Sch Pharm, Dongguan 523808, Peoples R China

[4] Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 2008年 / 46卷 / 09期

基金：

中国国家自然科学基金;

关键词：

NMR; H-1; C-13; 2D NMR; anthraquinone; secondary metabolites; structure elucidation;

D O I：

10.1002/mrc.2266

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new natural product named 6,8,1'-tri-O-methyl averantin has been isolated together with five known anthraquinones 1'-O-methyl averantin(2), 6,8-di-O-methyl averufin (3) averufin (4), versicolorin C (5) and 6,8-di-O-methyl averufanin (6) from a mangrove endophytic fungus ZSUH-36 collected from the South China Sea. NMR techniques including COSY, HMQC, and HMBC were used to elucidate the structures of these compounds. We report the unambiguous assignments of the H-1 and C-13 NMR spectra of the new compound 6,8,1'-tri-O-methyl averantin(l). Copyright (c) 2008 John Wiley & Sons, Ltd.

引用

页码：886 / 889

页数：4

共 11 条

[1]

Birkinshaw J H, 1966, J Chem Soc Perkin 1, V9, P855

[2] Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth [J].

Cha, TL ;

Qiu, L ;

Chen, CT ;

Wen, Y ;

Hung, MC .

CANCER RESEARCH, 2005, 65 (06) :2287-2295

[3] STRUCTURE OF A NEW METABOLITE OF ASPERGILLUS VERSICOLOR [J].

HAMASAKI, T ;

HATSUDA, Y ;

TERASHIM.N ;

RENBUTSU, M .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1965, 29 (07) :696-&

[4]

HOLKER JSE, 1966, CHEM COMMUN, P911

[5] INTERCALATING AGENTS WITH COVALENT BOND FORMING CAPABILITY - A NOVEL TYPE OF POTENTIAL ANTICANCER AGENTS .2. DERIVATIVES OF CHRYSOPHANOL AND EMODIN [J].

KOYAMA, M ;

TAKAHASHI, K ;

CHOU, TC ;

DARZYNKIEWICZ, Z ;

KAPUSCINSKI, J ;

KELLY, TR ;

WATANABE, KA .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (07) :1594-1599

[6] Five unique compounds:: Xyloketals from mangrove fungus Xylaria sp from the South China Sea coast [J].

Lin, YC ;

Wu, XY ;

Feng, SA ;

Jiang, GC ;

Luo, JH ;

Zhou, SN ;

Vrijmoed, LLP ;

Jones, EBG ;

Krohn, K ;

Steingröver, K ;

Zsila, F .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (19) :6252-6256

[7] STUDIES IN MYCOLOGICAL CHEMISTRY .13. AVERUFIN, A RED PIGMENT FROM ASPERGILLUS VERSICOLOR (VUILLEMIN) TIRABOSCHI [J].

PUSEY, DFG ;

ROBERTS, JC .

JOURNAL OF THE CHEMICAL SOCIETY, 1963, (JUL) :3542-&

[8] 1H and 13C NMR assignments for two anthraquinones and two xanthones from the mangrove fungus (ZSUH-36) [J].

Shao, Changlun ;

She, Zhigang ;

Guo, Zhiyong ;

Peng, Hong ;

Cai, Xiaoling ;

Zhou, Shining ;

Gu, Yucheng ;

Lin, Yongcheng .

MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (05) :434-438

[9] STABLE ISOTOPE STUDIES OF ANTHRAQUINONE INTERMEDIATES IN THE AFLATOXIN PATHWAY [J].

TOWNSEND, CA ;

CHRISTENSEN, SB .

TETRAHEDRON, 1983, 39 (21) :3575-3582

[10] Isolation and inhibitory activity against ERK Phosphorylation of hydroxyanthraquinones from rhubarb [J].

Zhou, X ;

Song, B ;

Jin, LH ;

Hu, DY ;

Diao, CL ;

Xu, GF ;

Zou, ZH ;

Yang, S .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (03) :563-568

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