Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity

被引:121
作者
Bendelac, A
Medzhitov, R
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA
[3] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA
关键词
D O I
10.1084/jem.20020073
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:F19 / F23
页数:5
相关论文
共 43 条
[1]   Toll-like receptors: critical proteins linking innate and acquired immunity [J].
Akira, S ;
Takeda, K ;
Kaisho, T .
NATURE IMMUNOLOGY, 2001, 2 (08) :675-680
[2]   Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway [J].
Basu, S ;
Binder, RJ ;
Suto, R ;
Anderson, KM ;
Srivastava, PK .
INTERNATIONAL IMMUNOLOGY, 2000, 12 (11) :1539-1546
[3]   Autoreactivity by design: Innate B and T lymphocytes [J].
Bendelac, A ;
Bonneville, M ;
Kearney, JF .
NATURE REVIEWS IMMUNOLOGY, 2001, 1 (03) :177-186
[4]   Help for cytotoxic-T-cell responses is mediated by CD40 signalling [J].
Bennett, SRM ;
Carbone, FR ;
Karamalis, F ;
Flavell, RA ;
Miller, JFAP ;
Heath, WR .
NATURE, 1998, 393 (6684) :478-480
[5]  
Carnaud C, 1999, J IMMUNOL, V163, P4647
[6]   Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells [J].
Cui, JQ ;
Watanabe, N ;
Kawano, T ;
Yamashita, M ;
Kamata, T ;
Shimizu, C ;
Kimura, M ;
Shimizu, E ;
Koike, J ;
Koseki, H ;
Tanaka, Y ;
Taniguchi, M ;
Nakayama, T .
JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (06) :783-792
[7]   C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity [J].
Dempsey, PW ;
Allison, MED ;
Akkaraju, S ;
Goodnow, CC ;
Fearon, DT .
SCIENCE, 1996, 271 (5247) :348-350
[8]  
Eberl G, 2000, EUR J IMMUNOL, V30, P985, DOI 10.1002/(SICI)1521-4141(200004)30:4<985::AID-IMMU985>3.0.CO
[9]  
2-E
[10]   Elements of immunity - The instructive role of innate immunity in the acquired immune response [J].
Fearon, DT ;
Locksley, RM .
SCIENCE, 1996, 272 (5258) :50-54