Reconstruction of individual thyroid doses to the Ukrainian subjects enrolled in the Chernobyl Tissue Bank

被引:17
作者
Likhtarov, I. [1 ,2 ]
Thomas, G. [3 ]
Kovgan, L. [1 ,2 ]
Masiuk, S. [1 ,2 ]
Chepurny, M. [1 ,2 ]
Ivanova, O. [1 ,2 ]
Gerasymenko, V. [1 ,2 ]
Tronko, M. [4 ]
Bogdanova, T. [4 ]
Bouville, A. [5 ]
机构
[1] Natl Acad Med Sci Ukraine, Natl Res Ctr Radiat Med, State Inst, UA-04050 Kiev, Ukraine
[2] Ukrainian Radiat Protect Inst, UA-04050 Kiev, Ukraine
[3] Univ London Imperial Coll Sci Technol & Med, London, England
[4] Natl Acad Med Sci Ukraine, VP Komisarenko Inst Endocrinol & Metab, State Inst, UA-04114 Kiev, Ukraine
[5] US Natl Canc Inst, Bethesda, MD 20892 USA
关键词
SHORT-LIVED RADIOIODINES; EXPOSED IN-UTERO; RADIOACTIVE CONTAMINATION; CANCER; I-131; ACCIDENT; CHILDREN; DISEASES; COHORT; RISK;
D O I
10.1093/rpd/nct096
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The Chernobyl Tissue Bank (CTB) is an organisation that collects and stores samples of tumoral thyroid tissue obtained from Ukrainian and Russian subjects who were treated surgically for a thyroid cancer and had been exposed to I-131 from the Chernobyl accident. By 2012, the CTB had collected specimens of thyroid tissue from 2267 residents of Ukraine for the purpose of radiation research. Arithmetic mean thyroid doses and uncertainties have been estimated for all but 24 subjects for whom residence at the time of exposure was not found. The subjects have been classified into six groups or sub-groups according to the type of dosimetry-related information that is available for each of them. Excluding the 325 subjects with negligible radiation exposure, the arithmetic mean of the thyroid dose over all subjects is estimated as 0.4 Gy, with individual values ranging from 1 mGy to 13 Gy. The uncertainties in the individual thyroid dose estimates, characterised by the geometric standard deviations of their probability distributions, range from 1.3 to 8.7, with an arithmetic mean of 3.2.
引用
收藏
页码:407 / 423
页数:17
相关论文
共 54 条
  • [1] [Anonymous], 1993, ANN ICRP, V23
  • [2] [Anonymous], 1990, ANN ICRP
  • [3] [Anonymous], 2003, NRSU97 MIN PUBL HLTH
  • [4] Contributions of short-lived radioiodines to thyroid doses received by evacuees from the Chernobyl area estimated using early in vivo activity measurements
    Balonov, M
    Kaidanovsky, G
    Zvonova, I
    Kovtun, A
    Bouville, A
    Luckyanov, N
    Voillequé, P
    [J]. RADIATION PROTECTION DOSIMETRY, 2003, 105 (1-4) : 593 - 599
  • [5] Barkhudarov R. M., 1989, MED ASPECTS CHERNOBY
  • [6] Risk of thyroid cancer after exposure to 131I in childhood
    Cardis, E
    Kesminiene, A
    Ivanov, V
    Malakhova, I
    Shibata, Y
    Khrouch, V
    Drozdovitch, V
    Maceika, E
    Zvonova, I
    Vlassov, O
    Bouville, A
    Goulko, G
    Hoshi, M
    Abrosimov, A
    Anoshko, J
    Astakhova, L
    Chekin, S
    Demidchik, E
    Galanti, R
    Ito, M
    Korobova, E
    Lushnikov, E
    Maksioutov, MA
    Masyakin, V
    Nerovnia, A
    Parshin, V
    Parshkov, E
    Piliptsevich, N
    Pinchera, A
    Polyakov, S
    Shabeka, N
    Suonio, E
    Tenet, V
    Tsyb, A
    Yamashita, S
    Williams, D
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (10): : 724 - 732
  • [7] Cristy M, 1987, ORNLTM8381V17
  • [8] Individual thyroid dose estimation for a case-control study of Chernobyl-related thyroid cancer among children of Belarus -: Part I:: 131I, short-lived radioiodines (132I, 133I, 135I), and short-lived radiotelluriums (131MTe and 132Te)
    Gavrilin, Y
    Khrouch, V
    Shinkarev, S
    Drozdovitch, V
    Minenko, V
    Shemiakina, E
    Ulanovsky, A
    Bouville, A
    Anspaugh, L
    Voillequé, P
    Luckyanov, N
    [J]. HEALTH PHYSICS, 2004, 86 (06): : 565 - 585
  • [9] Thyroid dose and thyroid cancer incidence after the Chernobyl accident: assessments for the Zhytomyr region (Ukraine)
    Goulko, GM
    Chepurny, NI
    Jacob, P
    Kairo, IA
    Likhtarev, IA
    Prohl, G
    Sobolev, BG
    [J]. RADIATION AND ENVIRONMENTAL BIOPHYSICS, 1998, 36 (04) : 261 - 273
  • [10] A Screening Study of Thyroid Cancer and Other Thyroid Diseases among Individuals Exposed in Utero to Iodine-131 from Chernobyl Fallout
    Hatch, M.
    Brenner, A.
    Bogdanova, T.
    Derevyanko, A.
    Kuptsova, N.
    Likhtarev, I.
    Bouville, A.
    Tereshchenko, V.
    Kovgan, L.
    Shpak, V.
    Ostroumova, E.
    Greenebaum, E.
    Zablotska, L.
    Ron, E.
    Tronko, M.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 94 (03) : 899 - 906