Multiple biological activities of curcumin: A short review

被引:1332
作者
Maheshwari, RK
Singh, AK
Gaddipati, J
Srimal, RC
机构
[1] Uniformed Serv Univ Life Sci, Ctr Combat Casualty & Life Sustainment Res, Dept Pathol, Bethesda, MD 20814 USA
[2] Ind Toxicol Res Ctr, Lucknow, Uttar Pradesh, India
关键词
curcumin; wound healing; anti-oxidant; angiogenesis; cancer;
D O I
10.1016/j.lfs.2005.12.007
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Turmieric (Curcuma longa rhizomes), commonly used as a spice is well documented for its medicinal properties in Indian and Chinese systems of medicine. It has been widely used for the treatment of several diseases. Epidemiological observations, though inconclusive, are suggestive that turmeric consumption may reduce the risk of some form of cancers and render other protective biological effects in humans. These biological effects of turmeric have been attributed to its constituent curcumin that has been widely studied for its anti-inflammatory, anti-angiogenic, antioxidant, wound healing and anti-cancer effects. As a result of extensive epidemiological, clinical, and animal studies several molecular mechanisms are emerging that elucidate multiple biological effects of curcumin. This review summarizes the most interesting in vitro and ill vivo studies on the biological effects of curcumin. Published by Elsevier Inc.
引用
收藏
页码:2081 / 2087
页数:7
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