Synthesis of 3,5-Bis(acrylaldehyde) Boron-dipyrromethene and Application in Detection of Cysteine and Homocysteine in Living Cells

被引:67
作者
Madhu, Sheri [1 ]
Gonnade, Rajesh [2 ]
Ravikanth, Mangalampalli [1 ]
机构
[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India
[2] Natl Chem Lab, Ctr Mat Characterizat, Pune 411008, Maharashtra, India
关键词
BODIPY DYES; SELECTIVE DETECTION; FLUORESCENT SENSOR; PROBES;
D O I
10.1021/jo4004597
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis, characterization, and spectral and electrochemical properties of 3,5-bis(acrylaldehyde) BODIPY are described. The compound exhibited higher selectivity toward cysteine/homocysteine than toward other amino acids and thiol-containing compounds as shown by absorption and emission titration experiments and by experiments in living cells.
引用
收藏
页码:5056 / 5060
页数:5
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