Ultrasonic-assisted reductive extraction of matrine from sophorae tonkinesis and its purification by macroporous resin column chromatography

被引：9
作者：
Cao, Qijin [1 ]
Wang, Lisheng [1 ]
Rashid, Haroon Ur [1 ]
Liang, Huimei [1 ]
Liu, Xu [1 ]
Xie, Peng [1 ]
机构：
[1] Guangxi Univ, Sch Chem & Chem Engn, 100 Daxue Rd, Nanning 530004, Guangxi, Peoples R China
来源：
SEPARATION SCIENCE AND TECHNOLOGY | 2018年 / 53卷 / 05期
关键词：
Macroporous resin; matrine; response surface methodology; ultrasonic-assisted reductive extraction; RESPONSE-SURFACE METHODOLOGY; FLAVESCENS AIT; OPTIMIZATION; ANTIOXIDANT; ALKALOIDS;
D O I：
10.1080/01496395.2017.1405040
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this work, ultrasonic-assisted reductive extraction of matrine from Sophorae tonkinesis was studied for the first time. During this process, sodium metabisulfite was added as a reducing agent in order to covert maximum amount of oxymatrine, sophocarpine, and oxysophocarpine to matrine. After optimization by response surface methodology, the extraction yield of matrine was found to be 2.03%, much higher than the yield obtained through traditional extraction method. After filtration, H103-macroporous adsorption resin column chromatography, concentration, and recrystallization, matrine with 98.2% purity was obtained.
引用
收藏
页码：745 / 755
页数：11
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