Ultrasound-assisted multi-component synthesis of indazolophthalazine derivatives

被引:5
|
作者
Vajargahy, Milad Pedarpour [1 ]
Dabiri, Minoo [1 ]
Magee, David [2 ]
Bazgir, Ayoob [1 ]
机构
[1] Shahid Beheshti Univ, Dept Chem, Tehran 1983963113, Iran
[2] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 5A3, Canada
关键词
Indazolophthalazine; Ultrasonic-assisted multi-component reaction; 2-Hydroxynaphthalene-1-4-dione; Phthalhydrazide; 2-5-Dihydroxycyclohexa-2-5-diene-1-4-dione; ORGANIC-SYNTHESIS; CHEMISTRY; EFFICIENT;
D O I
10.1007/s13738-015-0634-8
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An efficient multi-component synthesis of indazolophthalazine derivatives through the reaction of phthalhydrazide, 2-hydroxynaphthalene-1,4-dione or 2,5-dihydroxycyclohexa-2,5-diene-1,4-dione and active carbonyl compounds under ultrasonic irradiation is reported. This chemistry provides an efficient and promising synthetic strategy to diversity-oriented construction of the indazolophthalazine skeleton with potential biological activities.
引用
收藏
页码:1613 / 1621
页数:9
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