HDL Dysfunction Is the Answer in the Sphinx's Riddle?

被引:14
作者
Badimon, Juan J. [1 ]
Santos-Gallego, Carlos G. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Atherothrombosis Res Unit, Cardiovasc Inst, New York, NY 10029 USA
关键词
apo A-I; apo M; coronary artery disease; high-density lipoproteins; sphingosine-1-phosphate; SPHINGOSINE-1-PHOSPHATE ANALOG; SPHINGOSINE; 1-PHOSPHATE; DEFICIENT MICE; ATHEROSCLEROSIS; FTY720;
D O I
10.1016/j.jacc.2015.08.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1486 / 1488
页数:3
相关论文
共 15 条
[1]   Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy [J].
Boden, William E. ;
Probstfield, Jeffrey L. ;
Anderson, Todd ;
Chaitman, Bernard R. ;
Desvignes-Nickens, Patrice ;
Koprowicz, Kent ;
McBride, Ruth ;
Teo, Koon ;
Weintraub, William .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (24) :2255-2267
[2]   Hematopoietic Sphingosine 1-Phosphate Lyase Deficiency Decreases Atherosclerotic Lesion Development in LDL-Receptor Deficient Mice [J].
Bot, Martine ;
Van Veldhoven, Paul P. ;
de Jager, Saskia C. A. ;
Johnson, Jason ;
Nijstad, Niels ;
Van Santbrink, Peter J. ;
Westra, Marijke M. ;
Van Der Hoeven, Gerd ;
Gijbels, Marion J. ;
Mueller-Tidow, Carsten ;
Varga, Georg ;
Tietge, Uwe J. F. ;
Kuiper, Johan ;
Van Berkel, Theo J. C. ;
Nofer, Jerzy-Roch ;
Bot, Ilze ;
Biessen, Erik A. L. .
PLOS ONE, 2013, 8 (06)
[3]   Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M [J].
Christoffersen, Christina ;
Obinata, Hideru ;
Kumaraswamy, Sunil B. ;
Galvani, Sylvain ;
Ahnstrom, Josefin ;
Sevvana, Madhumati ;
Egerer-Sieber, Claudia ;
Muller, Yves A. ;
Hla, Timothy ;
Nielsen, Lars B. ;
Dahlback, Bjorn .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (23) :9613-9618
[4]   An abundant dysfunctional apolipoprotein A1 in human atheroma [J].
Huang, Ying ;
DiDonato, Joseph A. ;
Levison, Bruce S. ;
Schmitt, Dave ;
Li, Lin ;
Wu, Yuping ;
Buffa, Jennifer ;
Kim, Timothy ;
Gerstenecker, Gary S. ;
Gu, Xiaodong ;
Kadiyala, Chandra S. ;
Wang, Zeneng ;
Culley, Miranda K. ;
Hazen, Jennie E. ;
DiDonato, Anthony J. ;
Fu, Xiaoming ;
Berisha, Stela Z. ;
Peng, Daoquan ;
Nguyen, Truc T. ;
Liang, Shaohong ;
Chuang, Chia-Chi ;
Cho, Leslie ;
Plow, Edward F. ;
Fox, Paul L. ;
Gogonea, Valentin ;
Tang, W. H. Wilson ;
Parks, John S. ;
Fisher, Edward A. ;
Smith, Jonathan D. ;
Hazen, Stanley L. .
NATURE MEDICINE, 2014, 20 (02) :193-203
[5]   The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice [J].
Keul, Petra ;
Toelle, Markus ;
Lucke, Susann ;
Lipinski, Karin von Wnuck ;
Heusch, Gerd ;
Schuchardt, Mirjam ;
van der Giet, Markus ;
Levkau, Bodo .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (03) :607-613
[6]   High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors [J].
Kimura, T ;
Sato, K ;
Malchinkhuu, E ;
Tomura, H ;
Tamama, K ;
Kuwabara, A ;
Murakami, M ;
Okajima, F .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (07) :1283-1288
[7]   FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice [J].
Nofer, Jerzy-Roch ;
Bot, Martine ;
Brodde, Martin ;
Taylor, Paul J. ;
Salm, Paul ;
Brinkmann, Volker ;
van Berkel, Theo ;
Assmann, Gerd ;
Biessen, Erik A. L. .
CIRCULATION, 2007, 115 (04) :501-508
[8]   HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3 [J].
Nofer, JR ;
van der Giet, M ;
Tölle, M ;
Wolinska, I ;
Lipinski, KVW ;
Baba, HA ;
Tietge, UJ ;
Gödecke, A ;
Ishii, I ;
Kleuser, B ;
Schäfers, M ;
Fobker, M ;
Zidek, W ;
Assmann, G ;
Chun, J ;
Levkau, B .
JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (04) :569-581
[9]   SKI-II - a sphingosine kinase 1 inhibitor - exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet [J].
Poti, Francesco ;
Ceglarek, Uta ;
Burkhardt, Ralph ;
Simoni, Manuela ;
Nofer, Jerzy-Roch .
ATHEROSCLEROSIS, 2015, 240 (01) :212-215
[10]   HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events [J].
Rohatgi, Anand ;
Khera, Amit ;
Berry, Jarett D. ;
Givens, Edward G. ;
Ayers, Colby R. ;
Wedin, Kyle E. ;
Neeland, Ian J. ;
Yuhanna, Ivan S. ;
Rader, Daniel R. ;
de Lemos, James A. ;
Shaul, Philip W. .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (25) :2383-2393