HDL Dysfunction Is the Answer in the Sphinx's Riddle?

被引:14
作者
Badimon, Juan J. [1 ]
Santos-Gallego, Carlos G. [1 ]
机构
[1] Icahn Sch Med Mt Sinai, Atherothrombosis Res Unit, Cardiovasc Inst, New York, NY 10029 USA
关键词
apo A-I; apo M; coronary artery disease; high-density lipoproteins; sphingosine-1-phosphate; SPHINGOSINE-1-PHOSPHATE ANALOG; SPHINGOSINE; 1-PHOSPHATE; DEFICIENT MICE; ATHEROSCLEROSIS; FTY720;
D O I
10.1016/j.jacc.2015.08.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1486 / 1488
页数:3
相关论文
共 15 条
  • [1] Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy
    Boden, William E.
    Probstfield, Jeffrey L.
    Anderson, Todd
    Chaitman, Bernard R.
    Desvignes-Nickens, Patrice
    Koprowicz, Kent
    McBride, Ruth
    Teo, Koon
    Weintraub, William
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (24) : 2255 - 2267
  • [2] Hematopoietic Sphingosine 1-Phosphate Lyase Deficiency Decreases Atherosclerotic Lesion Development in LDL-Receptor Deficient Mice
    Bot, Martine
    Van Veldhoven, Paul P.
    de Jager, Saskia C. A.
    Johnson, Jason
    Nijstad, Niels
    Van Santbrink, Peter J.
    Westra, Marijke M.
    Van Der Hoeven, Gerd
    Gijbels, Marion J.
    Mueller-Tidow, Carsten
    Varga, Georg
    Tietge, Uwe J. F.
    Kuiper, Johan
    Van Berkel, Theo J. C.
    Nofer, Jerzy-Roch
    Bot, Ilze
    Biessen, Erik A. L.
    [J]. PLOS ONE, 2013, 8 (06):
  • [3] Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
    Christoffersen, Christina
    Obinata, Hideru
    Kumaraswamy, Sunil B.
    Galvani, Sylvain
    Ahnstrom, Josefin
    Sevvana, Madhumati
    Egerer-Sieber, Claudia
    Muller, Yves A.
    Hla, Timothy
    Nielsen, Lars B.
    Dahlback, Bjorn
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (23) : 9613 - 9618
  • [4] An abundant dysfunctional apolipoprotein A1 in human atheroma
    Huang, Ying
    DiDonato, Joseph A.
    Levison, Bruce S.
    Schmitt, Dave
    Li, Lin
    Wu, Yuping
    Buffa, Jennifer
    Kim, Timothy
    Gerstenecker, Gary S.
    Gu, Xiaodong
    Kadiyala, Chandra S.
    Wang, Zeneng
    Culley, Miranda K.
    Hazen, Jennie E.
    DiDonato, Anthony J.
    Fu, Xiaoming
    Berisha, Stela Z.
    Peng, Daoquan
    Nguyen, Truc T.
    Liang, Shaohong
    Chuang, Chia-Chi
    Cho, Leslie
    Plow, Edward F.
    Fox, Paul L.
    Gogonea, Valentin
    Tang, W. H. Wilson
    Parks, John S.
    Fisher, Edward A.
    Smith, Jonathan D.
    Hazen, Stanley L.
    [J]. NATURE MEDICINE, 2014, 20 (02) : 193 - 203
  • [5] The sphingosine-1-phosphate analogue FTY720 reduces atherosclerosis in apolipoprotein E-deficient mice
    Keul, Petra
    Toelle, Markus
    Lucke, Susann
    Lipinski, Karin von Wnuck
    Heusch, Gerd
    Schuchardt, Mirjam
    van der Giet, Markus
    Levkau, Bodo
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (03) : 607 - 613
  • [6] High-density lipoprotein stimulates endothelial cell migration and survival through sphingosine 1-phosphate and its receptors
    Kimura, T
    Sato, K
    Malchinkhuu, E
    Tomura, H
    Tamama, K
    Kuwabara, A
    Murakami, M
    Okajima, F
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2003, 23 (07) : 1283 - 1288
  • [7] FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice
    Nofer, Jerzy-Roch
    Bot, Martine
    Brodde, Martin
    Taylor, Paul J.
    Salm, Paul
    Brinkmann, Volker
    van Berkel, Theo
    Assmann, Gerd
    Biessen, Erik A. L.
    [J]. CIRCULATION, 2007, 115 (04) : 501 - 508
  • [8] HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3
    Nofer, JR
    van der Giet, M
    Tölle, M
    Wolinska, I
    Lipinski, KVW
    Baba, HA
    Tietge, UJ
    Gödecke, A
    Ishii, I
    Kleuser, B
    Schäfers, M
    Fobker, M
    Zidek, W
    Assmann, G
    Chun, J
    Levkau, B
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (04) : 569 - 581
  • [9] SKI-II - a sphingosine kinase 1 inhibitor - exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet
    Poti, Francesco
    Ceglarek, Uta
    Burkhardt, Ralph
    Simoni, Manuela
    Nofer, Jerzy-Roch
    [J]. ATHEROSCLEROSIS, 2015, 240 (01) : 212 - 215
  • [10] HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events
    Rohatgi, Anand
    Khera, Amit
    Berry, Jarett D.
    Givens, Edward G.
    Ayers, Colby R.
    Wedin, Kyle E.
    Neeland, Ian J.
    Yuhanna, Ivan S.
    Rader, Daniel R.
    de Lemos, James A.
    Shaul, Philip W.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (25) : 2383 - 2393