Survival data on timing of resection of liver metastases in colorectal cancer patients

被引：0

作者：

Nitsche, Ulrich ^{[1
]}

Weber, Constance ^{[1
]}

Kaufmann, Benedikt ^{[1
]}

Figura, Guido von ^{[2
]}

Assfalg, Volker ^{[1
]}

Miller, Gregor ^{[3
]}

Friess, Helmut ^{[1
]}

Hueser, Norbert ^{[1
]}

Hartmann, Daniel ^{[1
]}

机构：

[1] Tech Univ Munich, TUM Sch Med, Dept Surg, Klinikum Rechts Isar, Munich, Germany

[2] Tech Univ Munich, TUM Sch Med, Dept Med 2, Klinikum Rechts Isar, Munich, Germany

[3] Tech Univ Munich, Dept Math, Munich, Germany

来源：

DATA IN BRIEF | 2020年 / 31卷

关键词：

Colorectal cancer; Surgery; Liver metastases; Synchronous resection; Staged resection; Survival;

D O I：

10.1016/j.dib.2020.105973

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Between 2007 and 2016, 140 consecutive patients who underwent resection of colorectal cancer with simultaneous liver metastases at a single university hospital were retrospectively analysed. In order to gather information regarding potential survival differences for n = 68 simultaneous versus n = 72 staged resections of the colorectal primary tumor and the liver metastases, Clinical, histopathological, serological, and survival data were compared for those two patient groups. The rate of simultaneous tumor resections increased from approximately 25% in 2007 to 75% in 2016. There was no difference in tumor specific survival for patients with simultaneous vs. staged resection (p = 0.631). This effect continued after excluding patients with extra hepatic metastases ( p = 0.440). Further, neoadjuvant treatment did not lead to differences in the tumor-specific survival (p = 0.123). Factors associated with an increased tumor specific survival were low ASA score ( p < 0.001), low number of tumor-affected lymph nodes ( p < 0.001), histological grading G1/2 (p = 0.001), and a low number of liver metastases (p = 0.044). There was no significant survival difference for the primary tumor stage (pT), the Clavien-Dindo complication rate, the resection status (R0), and minor versus major hepatectomies. (c) 2020 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license. (http://creativecommons.org/licenses/by/4.0/ )

引用

页数：5