Home-based step training using videogame technology in people with Parkinson's disease: a single-blinded randomised controlled trial

被引:64
作者
Song, Jooeun [1 ,2 ]
Paul, Serene S. [1 ,3 ]
Caetano, Maria Joana D. [4 ]
Smith, Stuart [5 ]
Dibble, Leland E. [6 ]
Love, Rachelle [1 ]
Schoene, Daniel [7 ]
Menant, Jasmine C. [4 ]
Sherrington, Cathie [3 ]
Lord, Stephen R. [4 ]
Canning, Colleen G. [1 ]
Allen, Natalie E. [1 ]
机构
[1] Univ Sydney, Fac Hlth Sci, Sydney, NSW, Australia
[2] Univ Technol Sydney, Grad Sch Hlth, Sydney, NSW, Australia
[3] Univ Sydney, Sch Publ Hlth, Musculoskeletal Hlth Sydney, Sydney, NSW, Australia
[4] Univ New South Wales, Neurosci Res Australia, Falls Balance & Injury Res Ctr, Sydney, NSW, Australia
[5] Southern Cross Univ, Coffs Harbour, NSW, Australia
[6] Univ Utah, Dept Phys Therapy, Salt Lake City, UT USA
[7] Friedrich Alexander Univ Erlangen Nurnberg, Inst Biomed Ageing, Erlangen, Germany
基金
英国医学研究理事会;
关键词
Parkinson's disease; exergames; stepping performance; home-based training; MINI-MENTAL-STATE; LEG MUSCLE POWER; EXERCISE PROGRAM; FALLS RISK; PERFORMANCE; REDUCE; GAIT;
D O I
10.1177/0269215517721593
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objectives: To determine whether 12-week home-based exergame step training can improve stepping performance, gait and complementary physical and neuropsychological measures associated with falls in Parkinson's disease. Design: A single-blinded randomised controlled trial. Setting: Community (experimental intervention), university laboratory (outcome measures). Subjects: Sixty community-dwelling people with Parkinson's disease. Interventions: Home-based step training using videogame technology. Main measures: The primary outcomes were the choice stepping reaction time test and Functional Gait Assessment. Secondary outcomes included physical and neuropsychological measures associated with falls in Parkinson's disease, number of falls over sixmonths and self-reported mobility and balance. Results: Post intervention, there were no differences between the intervention (n=28) and control (n=25) groups in the primary or secondary outcomes except for the Timed Up and Go test, where there was a significant difference in favour of the control group (P=0.02). Intervention participants reported mobility improvement, whereas control participants reported mobility deteriorationbetween-group difference on an 11-point scale=0.9 (95% confidence interval: -1.8 to -0.1, P=0.03). Interaction effects between intervention and disease severity on physical function measures were observed (P=0.01 to P=0.08) with seemingly positive effects for the low-severity group and potentially negative effects for the high-severity group. Conclusion: Overall, home-based exergame step training was not effective in improving the outcomes assessed. However, the improved physical function in the lower disease severity intervention participants as well as the self-reported improved mobility in the intervention group suggest home-based exergame step training may have benefits for some people with Parkinson's disease.
引用
收藏
页码:299 / 311
页数:13
相关论文
共 35 条
[1]   Exercise and Motor Training in People with Parkinson's Disease: A Systematic Review of Participant Characteristics, Intervention Delivery, Retention Rates, Adherence, and Adverse Events in Clinical Trials [J].
Allen, Natalie E. ;
Sherrington, Catherine ;
Suriyarachchi, Gayanthi D. ;
Paul, Serene S. ;
Song, Jooeun ;
Canning, Colleen G. .
PARKINSONS DISEASE, 2012, 2012
[2]   A randomised controlled trial of a home based exercise programme to reduce the risk of falling among people with Parkinson's disease [J].
Ashburn, Ann ;
Fazakarley, Louise ;
Ballinger, Claire ;
Pickering, Ruth ;
McLellan, Lindsay D. ;
Fitton, Carolyn .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2007, 78 (07) :678-684
[3]  
Barry G, 2014, J NEUROENG REHABIL, V11, DOI [10.1186/1743-0003-11-33, 10.1186/1743-0003-11-60]
[4]  
Caetano MJ, 2016, J GERONTOL A-BIOL, DOI [10.1093/gerona/glw171., DOI 10.1093/GERONA/GLW171.]
[5]   Exercise for falls prevention in Parkinson disease A randomized controlled trial [J].
Canning, Colleen G. ;
Sherrington, Catherine ;
Lord, Stephen R. ;
Close, Jacqueline C. T. ;
Heritier, Stephane ;
Heller, Gillian Z. ;
Howard, Kirsten ;
Allen, Natalie E. ;
Latt, Mark D. ;
Murray, Susan M. ;
O'Rourke, Sandra D. ;
Paul, Serene S. ;
Song, Jooeun ;
Fung, Victor S. C. .
NEUROLOGY, 2015, 84 (03) :304-312
[6]   MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[7]   The Effects of Practice on the Concurrent Performance of a Speech and Postural Task in Persons with Parkinson Disease and Healthy Controls [J].
Foreman, K. Bo ;
Sondrup, Stuart ;
Dromey, Christopher ;
Jarvis, Eon ;
Nissen, Shawn ;
Dibble, Leland E. .
PARKINSONS DISEASE, 2013, 2013
[8]   Calibration of unified Parkinson's disease rating scale scores to Movement Disorder Society-unified Parkinson's disease rating scale scores [J].
Goetz, Christopher G. ;
Stebbins, Glenn T. ;
Tilley, Barbara C. .
MOVEMENT DISORDERS, 2012, 27 (10) :1239-1242
[9]   The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years [J].
Hely, Mariese A. ;
Reid, Wayne G. J. ;
Adena, Michael A. ;
Halliday, Glenda A. ;
Morris, John G. L. .
MOVEMENT DISORDERS, 2008, 23 (06) :837-844
[10]   The contribution of trail making to the prediction of performance-based instrumental activities of daily living in Parkinson's disease without dementia [J].
Higginson, Christopher I. ;
Lanni, Kimberly ;
Sigvardt, Karen A. ;
Disbrow, Elizabeth A. .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 2013, 35 (05) :530-539