Cerebral aspergillosis caused by Aspergillus ustus following orthotopic heart transplantation: case report and review of the literature

被引：15

作者：

Florescu, Diana F. ^{[1
]}

Iwen, Peter C. ^{[2
]}

Hill, Lisa A.

Dumitru, Ioana ^{[3
]}

Quader, Mohammed A. ^{[4
]}

Kalil, Andre C.

Freifeld, Alison G.

机构：

[1] Univ Nebraska, Med Ctr, Dept Internal Med,Sect Infect Dis, Immunocompromised Host Infect Dis Program, Omaha, NE 68198 USA

[2] Univ Nebraska, Med Ctr, Dept Pathol & Microbiol, Omaha, NE 68198 USA

[3] Univ Nebraska, Med Ctr, Dept Internal Med, Cardiol Sect, Omaha, NE 68198 USA

[4] Univ Nebraska, Med Ctr, Dept Internal Med, Sect Cardiothorac Surg, Omaha, NE 68198 USA

来源：

CLINICAL TRANSPLANTATION | 2009年 / 23卷 / 01期

关键词：

Aspergillus ustus; cerebral aspergillosis; heart transplant; COMBINATION ANTIFUNGAL THERAPY; MOLD INFECTIONS; AMPHOTERICIN-B; INVASIVE ASPERGILLOSIS; VORICONAZOLE; CASPOFUNGIN; RECIPIENTS; IDENTIFICATION; REGIONS;

D O I：

10.1111/j.1399-0012.2008.00895.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

This report describes the first case of cerebral aspergillosis in a heart transplantation patient caused by Aspergillus ustus and reviews 15 previously reported cases of invasive aspergillosis in immunocompromised hosts caused by this mold. The utility of molecular analysis for the identification of unusual fungal pathogens is also described. The refractory nature of A. ustus to treatment is similar to other Aspergillus species and treatment options are reviewed.

引用

页码：116 / 120

页数：5

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