Beneficial Effects of Resveratrol on Atherosclerosis

被引：93

作者：

Fan, Enguo ^{[1
,3
]}

Zhang, Lijuan ^{[2
]}

Jiang, Sha ^{[1
]}

Bai, Yuhua ^{[1
]}

机构：

[1] Nankai Univ, Coll Life Sci, Tianjin 300071, Peoples R China

[2] Tianjin Univ Tradit Chinese Med, Tianjin, Peoples R China

[3] Univ Halle Wittenberg, Inst Plant & Cell Physiol, Halle, Germany

来源：

JOURNAL OF MEDICINAL FOOD | 2008年 / 11卷 / 04期

关键词：

advancement; atherosclerosis; beneficial effects; resveratrol;

D O I：

10.1089/jmf.2007.0091

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Atherosclerosis, a progressive disease characterized by the accumulation of lipids and fibrous elements in the arteries, is a most important contributor to cardiovascular diseases. Resveratrol is a naturally occurring phytopolyphenol compound and shows the ability to reduce the risk of cardiovascular diseases. In this review, beneficial effects of resveratrol on the initiation and progression of atherosclerosis, including regulation of vasodilator and vasoconstrictor production, inhibition of oxidative stress/reactive oxygen species generation, anti-inflammation, inhibition of modification of low-density lipoproteins, anti-platelet aggregation, and its abilities to impede progression and modulate complications of atherosclerosis, are discussed.

引用

页码：610 / 614

页数：5

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