Bioconversion of lignocellulose: inhibitors and detoxification

被引：1049

作者：

Jonsson, Leif J. ^{[1
]}

Alriksson, Bjorn ^{[2
]}

Nilvebrant, Nils-Olof ^{[3
]}

机构：

[1] Umea Univ, Dept Chem, SE-90187 Umea, Sweden

[2] Processum Biorefinery Initiat AB, SE-89122 Omskoldsvik, Sweden

[3] Borregaard, N-1701 Sarpsborg, Norway

来源：

BIOTECHNOLOGY FOR BIOFUELS | 2013年 / 6卷

基金：

瑞典研究理事会;

关键词：

STEAM-EXPLODED POPLAR; SACCHAROMYCES-CEREVISIAE; ETHANOL-PRODUCTION; FERMENTATION INHIBITORS; BIOETHANOL PRODUCTION; ENZYMATIC-HYDROLYSIS; PICHIA-STIPITIS; WHEAT-STRAW; CORN STOVER; BIOLOGICAL DETOXIFICATION;

D O I：

10.1186/1754-6834-6-16

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Bioconversion of lignocellulose by microbial fermentation is typically preceded by an acidic thermochemical pretreatment step designed to facilitate enzymatic hydrolysis of cellulose. Substances formed during the pretreatment of the lignocellulosic feedstock inhibit enzymatic hydrolysis as well as microbial fermentation steps. This review focuses on inhibitors from lignocellulosic feedstocks and how conditioning of slurries and hydrolysates can be used to alleviate inhibition problems. Novel developments in the area include chemical in-situ detoxification by using reducing agents, and methods that improve the performance of both enzymatic and microbial biocatalysts.

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页数：10

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