Corpus callosotomy in a patient of hemimegalencephaly and Lennox-Gastaut syndrome

被引:0
作者
Kwan, Shang-Yeong [2 ,3 ]
Shyu, Hann-Yeh [4 ]
Lin, Ji-Ho [1 ,5 ]
Wong, Tai-Tong [2 ,3 ]
Chang, Kai-Ping [2 ,3 ]
Yiu, Chun-Hing [2 ,3 ]
机构
[1] Tao Yuan Gen Hosp, Dept Hlth, Dept Neurol, Tao Yuan, Taiwan
[2] Natl Yang Ming Univ, Taipei Vet Gen Hosp, Pediat Epilepsy Surg Grp, Taipei 112, Taiwan
[3] Natl Yang Ming Univ, Sch Med, Taipei 112, Taiwan
[4] Armed Forces Tao Yuan Gen Hosp, Dept Med, Neurol Sect, Tao Yuan, Taoyuan County, Taiwan
[5] Fu Jen Catholic Univ, Sch Med, Taipei, Taipei County, Taiwan
关键词
Corpus callosotomy; Epilepsy; Generalized cortical dysplasia; Hemimegalencephaly; Lennox-Gastaut syndrome;
D O I
10.1016/j.braindev.2008.03.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report the case of a girl with hemimegalencephaly (HME) and Lennox-Gastaut syndrome (LGS) treated by callosotomy at 1 year of age. Over 10 years, her seizure frequency and severity decreased markedly. Hemispherectomy is the main surgical option for HME although HME appears to correlate with a less favorable seizure outcome. However, the clinical presentation of LGS and possible generalized cortical dysplasia, which is indicative of a secondarily generalized epilepsy, might predict a favorable surgical outcome of corpus callosotomy in patients of HME, as in our case. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:643 / 646
页数:4
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