Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system

被引:3
作者
Maximov, V. V. [1 ]
Arman, I. P. [1 ]
Tarantul, V. Z. [1 ]
机构
[1] Russian Acad Sci, Inst Genet Mol, Moscow 123182, Russia
基金
俄罗斯基础研究基金会;
关键词
D O I
10.1134/S1022795406020141
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Humanine is a human neuroprotective peptide with a wide action spectrum. To analyze molecular mechanisms of humanin functioning, a search for proteins interacting with this peptide was conducted using yeast two-hybrid system. Screening of human fetal brain cDNA library identified seven proteins with different functions that specifically interacted with humanin.
引用
收藏
页码:208 / 211
页数:4
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