Retrospective Molecular Analysis of DIM-1 Metallo-β-Lactamase Discovered in Pseudomonas stutzeri from India in 2000

被引：10

作者：

Deshpande, Lalitagauri M. ^{[1
]}

Jones, Ronald N. ^{[1
,2
]}

Woosley, Leah N. ^{[1
]}

Castanheira, Mariana ^{[1
]}

机构：

[1] JMI Labs, North Liberty, IA USA

[2] Tufts Univ, Sch Med, Boston, MA 02111 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2014年 / 58卷 / 01期

关键词：

CARBAPENEMASE GENES; MULTIPLEX PCR; IDENTIFICATION;

D O I：

10.1128/AAC.01541-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Among 220 clinical isolates of Gram-negative bacilli collected in India during 2000, 22 strains showing elevated imipenem MICs were evaluated for carbapenemase production. One DIM-1-producing Pseudomonas stutzeri isolate was detected, and no other carbapenemase-encoding genes were identified. This detection of a DIM-1-producing P. stutzeri isolate from India predating the finding of this gene in the index Dutch strain and the very recent detection of DIM-1 in Africa suggest an unidentified environmental source of this metallo-beta-lactamase gene.

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收藏

页码：596 / 598

页数：3

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