Atypical fractures: An issue of concern or a myth?

被引：9
|
作者：
Al-Ashqar, Mohammad [1 ]
Panteli, Michalis [2 ]
Chakrabarty, Gautam [3 ]
Giannoudis, Peter V. [2 ]
机构：
[1] Leeds Gen Infirm, Dept Trauma & Orthopaed, Leeds, W Yorkshire, England
[2] Univ Leeds, Sch Med, Acad Dept Trauma & Orthopaed, Clarendon Wing,Level A,Great George St, Leeds LS1 3EX, W Yorkshire, England
[3] Univ Huddersfield, Dept Trauma & Orthopaed, Huddersfield Royal Infirm, Huddersfield, W Yorkshire, England
来源：
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2018年 / 49卷 / 03期
关键词：
Atypical; Osteoporosis; Stress/insufficiency fractures; Bisphosphonates; SUBTROCHANTERIC STRESS-FRACTURES; SUPPRESSED BONE TURNOVER; FEMORAL-SHAFT FRACTURES; POSTMENOPAUSAL WOMEN; IN-VITRO; BISPHOSPHONATE USE; SALMON-CALCITONIN; OSTEOPOROSIS; RISK; ALENDRONATE;
D O I：
10.1016/j.injury.2017.12.016
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Atypical Femoral Fractures (AFF) represent fractures located between the lesser trochanter and the supracondylar flare of a femur. An increasing pool of evidence supports their association with the prolonged use of bisphosphonates, even though a direct correlation is yet to be proved. The purpose of this review is to encapsulate the current evidence associating bisphosphonate use and the development of AFFs, the clinical features related to their presentation, as well as to report the armamentarium of strategies available in the prevention and treatment of AFFs. Based on these evidence, we propose a management algorithm for AFFs, that can serve as a guide for patients presenting with this condition. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：649 / 655
页数：7
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