Prevalence of systolic and diastolic dysfunction in patients with type 1 diabetes without known heart disease: the Thousand & 1 Study

被引：77

作者：

Jensen, Magnus T. ^{[1
,2
]}

Sogaard, Peter ^{[1
]}

Andersen, Henrik U. ^{[2
]}

Bech, Jan ^{[1
]}

Hansen, Thomas F. ^{[1
]}

Galatius, Soren ^{[1
]}

Jorgensen, Peter G. ^{[1
,3
]}

Biering-Sorensen, Tor ^{[1
]}

Mogelvang, Rasmus ^{[1
]}

Rossing, Peter ^{[2
,4
,5
]}

Jensen, Jan S. ^{[1
,3
]}

机构：

[1] Univ Copenhagen, Gentofte Hosp, Dept Cardiol, DK-2900 Hellerup, Denmark

[2] Steno Diabet Ctr, DK-2820 Gentofte, Denmark

[3] Univ Copenhagen, Inst Clin Med, Fac Hlth Sci, Copenhagen, Denmark

[4] Univ Copenhagen, Novo Nordisk Fdn, Ctr Basic Metab Res, Fac Hlth Sci, Copenhagen, Denmark

[5] Univ Aarhus, Fac Hlth, Aarhus, Denmark

来源：

DIABETOLOGIA | 2014年 / 57卷 / 04期

关键词：

Albuminuria; Diabetes; Diastolic dysfunction; Echocardiography; Heart disease; Heart failure; Prevention; Systolic dysfunction; Type; 1; diabetes; CARDIOVASCULAR-DISEASE; VENTRICULAR DYSFUNCTION; GENERAL-POPULATION; NEPHROPATHY; FAILURE; RECOMMENDATIONS; MORTALITY; ECHOCARDIOGRAPHY; CARDIOMYOPATHY; PREDICTOR;

D O I：

10.1007/s00125-014-3164-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aims/hypothesis Heart failure is one of the leading causes of mortality in type 1 diabetes. Early identification is vitally important. We sought to determine the prevalence and clinical characteristics associated with subclinical impaired systolic and diastolic function in type 1 diabetes patients without known heart disease. Methods In this cross-sectional examination of 1,093 type 1 diabetes patients without known heart disease, randomly selected from the Steno Diabetes Center, complete clinical and echocardiographic examinations were performed and analysed in uni- and multivariable regression models. Results The mean (SD) age was 49.6 (15) years, 53% of participants were men, and the mean duration of diabetes was 25.5

引用

页码：672 / 680

页数：9

共 27 条

[21] Early predictors of myocardial disease in children and adolescents with type 1 diabetes mellitus [J].