Sonographic Substantia Nigra Hypoechogenicity in Polyneuropathy and Restless Legs Syndrome

被引:14
|
作者
Godau, Jana [1 ]
Manz, Almut [1 ]
Wevers, Anne-Kathrin [1 ]
机构
[1] Univ Tubingen, Hertie Inst Clin Brain Res, Dept Neurodegenerat, D-72076 Tubingen, Germany
关键词
ultrasound; restless legs syndrome; neuropathy; TRANSCRANIAL ULTRASOUND; PARKINSONS-DISEASE; DIFFERENTIAL-DIAGNOSIS; IRON; EPIDEMIOLOGY; POPULATION; DEFINITION; RLS;
D O I
10.1002/mds.22391
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Substantia nigra (SN) hypoechogenicity assessed by transcranial B-mode sonography (TCS) is typical for idiopathic restless legs syndrome (RLS). Here, we investigated whether SN hypoechogenicity may differentiate between polyneuropathy (PNP) patients with and without RLS. Seventy-five patients with PNP, 65 healthy controls, and 75 patients with idiopathic RLS were investigated. A total of 41.2% patients with PNP additionally suffered from RLS. A total of 44.1% patients with PNP, 10.2% of healthy controls, and 91.2% of patients with idiopathic RLS exhibited SIN hypoechogenicity. SN echogenicity did not differ significantly between PNP patients with and without RLS. Thus, TCS seems not suitable for the diagnosis of RLS in patients with PNP. (c) 2008 Movement Disorder Society.
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页码:133 / 137
页数:5
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