Supramolecular Hydrogel Based on Graphene Oxides for Controlled Release System

被引：20
|
作者：
Cheng, Qian-Yi [1 ,2 ]
Han, Bao-Hang [1 ]
机构：
[1] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[2] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
来源：
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2013年 / 13卷 / 02期
基金：
美国国家科学基金会;
关键词：
Graphene Oxide; Drug Delivery; Supramolecular Hydrogel; Control Release; Nanomaterials; DRUG-DELIVERY; COPOLYMERS; SHEETS;
D O I：
10.1166/jnn.2013.6058
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Supramolecular hydrogel drug delivery system that composed of F127 modified small-sized graphene oxide (F127-SGO) and alpha-CD was prepared and the controlled release behavior was studied using doxorubicin hydrochloride (DOX) as a model drug. As compared with native hydrogel formed from F127 and alpha-CD, the SGO-containing hybrid hydrogel system shows multiple binding sites to load drug molecules and a more controllable release process that facilitates to tune the drug delivery system. These properties make the supramolecular hydrogel a potential candidate for controlled drug delivery system.
引用
收藏
页码：755 / 760
页数：6
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