Pathology and images of radiation-induced hepatitis: a review article

被引：38

作者：

Takamatsu, Shigeyuki ^{[1
]}

Kozaka, Kazuto ^{[2
]}

Kobayashi, Satoshi ^{[2
]}

Yoneda, Norihide ^{[2
]}

Yoshida, Kotaro ^{[2
]}

Inoue, Dai ^{[2
]}

Kitao, Azusa ^{[2
]}

Ogi, Takahiro ^{[2
]}

Minami, Tetsuya ^{[2
]}

Kouda, Wataru ^{[2
]}

Kumano, Tomoyasu ^{[1
]}

Fuwa, Nobukazu ^{[3
]}

Matsui, Osamu ^{[2
]}

Gabata, Toshifumi ^{[2
]}

机构：

[1] Kanazawa Univ, Grad Sch Med, Dept Radiotherapy, 13-1 Takara Machi, Kanazawa, Ishikawa 9208641, Japan

[2] Kanazawa Univ, Grad Sch Med, Dept Radiol, 13-1 Takara Machi, Kanazawa, Ishikawa 9208641, Japan

[3] Ise Red Cross Hosp, Dept Radiotherapy, 1-471-2 Funae, Ise, Mie 5168512, Japan

来源：

JAPANESE JOURNAL OF RADIOLOGY | 2018年 / 36卷 / 04期

关键词：

Radiation-induced liver disease; Focal liver injury; Focal liver reaction; Hepatocellular carcinoma; Pathology; Threshold dose; INDUCED LIVER-DISEASE; RESPONSE EVALUATION CRITERIA; 3-DIMENSIONAL CONFORMAL RADIOTHERAPY; PROTON-BEAM THERAPY; GD-EOB-DTPA; HEPATOCELLULAR-CARCINOMA; SOLID TUMORS; VENOOCCLUSIVE DISEASE; INJURY; CT;

D O I：

10.1007/s11604-018-0728-1

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Recent advances in highly conformal radiotherapies greatly extend the indications for radiotherapy of liver tumors. However, because of poor tolerance to hepatic radiation, estimation of the intensity of irradiation of the liver is important, particularly for a cirrhotic liver. Knowledge of radiation-induced hepatitis is important for understanding how to optimize hepatic radiation therapy. Pathological changes of the irradiated liver, which include perivenular fibrosis, sinusoidal obstruction, and damage to Kupffer cells and hepatocytes, can be visualized using clinical imaging techniques. This review article discusses and illustrates the pathological and radiological changes of hepatic tumors and the surrounding parenchyma of the irradiated liver.

引用

页码：241 / 256

页数：16

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