Mucosal-Associated Invariant T Cells as a Possible Target to Suppress Secondary Infections at COVID-19

被引：9

作者：

Akasov, Roman A. ^{[1
,2
,3
]}

Khaydukov, Evgeny V. ^{[1
,3
]}

机构：

[1] Russian Acad Sci, Fed Sci Res Ctr Crystallog & Photon, Moscow, Russia

[2] Natl Univ Sci & Technol MISIS, Lab Biomed Nanomat, Moscow, Russia

[3] Sechenov Univ, Inst Mol Med, Ctr Biomed Engn, Moscow, Russia

来源：

FRONTIERS IN IMMUNOLOGY | 2020年 / 11卷

关键词：

COVID-19; SARS-CoV-2; mucosal associated invariant T cells; riboflavin; flavin mononucleotide; FMN riboswitch; immunomodulation; cytokines; MAIT CELLS; RIBOFLAVIN SUPPLEMENTATION; DISEASE; RIBOSWITCHES;

D O I：

10.3389/fimmu.2020.01896

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页数：4

共 32 条

[1] Novel Riboswitch-Binding Flavin Analog That Protects Mice against Clostridium difficile Infection without Inhibiting Cecal Flora [J].

Blount, Kenneth F. ;

Megyola, Cynthia ;

Plummer, Mark ;

Osterman, David ;

O'Connell, Tim ;

Aristoff, Paul ;

Quinn, Cheryl ;

Chrusciel, R. Alan ;

Poel, Toni J. ;

Schostarez, Heinrich J. ;

Stewart, Catherine A. ;

Walker, Daniel P. ;

Wuts, Peter G. M. ;

Breaker, Ronald R. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2015, 59 (09) :5736-5746

[2] MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation [J].

Bottcher, Katrin ;

Rombouts, Krista ;

Saffioti, Francesca ;

Roccarina, Davide ;

Rosselli, Matteo ;

Hall, Andrew ;

TuVinh Luong ;

Tsochatzis, Emmanuel A. ;

Thorburn, Douglas ;

Pinzani, Massimo .

HEPATOLOGY, 2018, 68 (01) :172-186

[3] Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals [J].

Chen, Z. ;

Wang, H. ;

D'Souza, C. ;

Sun, S. ;

Kostenko, L. ;

Eckle, S. B. G. ;

Meehan, B. S. ;

Jackson, D. C. ;

Strugnell, R. A. ;

Cao, H. ;

Wang, N. ;

Fairlie, D. P. ;

Liu, L. ;

Godfrey, D. I. ;

Rossjohn, J. ;

McCluskey, J. ;

Corbett, A. J. .

MUCOSAL IMMUNOLOGY, 2017, 10 (01) :58-68

[4] Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis [J].

Chiba, Asako ;

Tajima, Ryohsuke ;

Tomi, Chiharu ;

Miyazaki, Yusei ;

Yamamura, Takashi ;

Miyake, Sachiko .

ARTHRITIS AND RHEUMATISM, 2012, 64 (01) :153-161

[5] Co-infections: potentially lethal and unexplored in COVID-19 [J].

Cox, Michael J. ;

Loman, Nicholas ;

Bogaert, Debby ;

O'Grady, Justin .

LANCET MICROBE, 2020, 1 (01) :E11-E11

[6] Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection [J].

D'Souza, Criselle ;

Pediongco, Troi ;

Wang, Huimeng ;

Scheerlinck, Jean-Pierre Y. ;

Kostenko, Lyudmila ;

Esterbauer, Robyn ;

Stent, Andrew W. ;

Eckle, Sidonia B. G. ;

Meehan, Bronwyn S. ;

Strugnell, Richard A. ;

Cao, Hanwei ;

Liu, Ligong ;

Mak, Jeffrey Y. W. ;

Lovrecz, George ;

Lu, Louis ;

Fairlie, David P. ;

Rossjohn, Jamie ;

McCluskey, James ;

Every, Alison L. ;

Chen, Zhenjun ;

Corbett, Alexandra J. .

JOURNAL OF IMMUNOLOGY, 2018, 200 (05) :1901-1916

[7] Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19) [J].

Diao, Bo ;

Wang, Chenhui ;

Tan, Yingjun ;

Chen, Xiewan ;

Liu, Ying ;

Ning, Lifen ;

Chen, Li ;

Li, Min ;

Liu, Yueping ;

Wang, Gang ;

Yuan, Zilin ;

Feng, Zeqing ;

Zhang, Yi ;

Wu, Yuzhang ;

Chen, Yongwen .

FRONTIERS IN IMMUNOLOGY, 2020, 11

[8] The biology and functional importance of MAIT cells [J].

Godfrey, Dale, I ;

Koay, Hui-Fern ;

McCluskey, James ;

Gherardin, Nicholas A. .

NATURE IMMUNOLOGY, 2019, 20 (09) :1110-1128

[9] Role of MAIT cells in pulmonary bacterial infection [J].

Hartmann, Nadine ;

Harriff, Melanie J. ;

McMurtrey, Curtis P. ;

Hildebrand, William H. ;

Lewinsohn, David M. ;

Kronenberg, Mitchell .

MOLECULAR IMMUNOLOGY, 2018, 101 :155-159

[10]

Jouan Y., 2020, FUNCTIONAL ALTERATIO, DOI [10.1101/2020.05.03.20089300, DOI 10.1101/2020.05.03.20089300]

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