Herpes simplex virus hepatitis causing acute liver dysfunction and thrombocytopenia in pregnancy

被引：20
|
作者：
Allen, RH
Tuomala, RE
机构：
[1] Brigham & Womens Hosp, Dept Obstet & Gynecol, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Boston, MA 02114 USA
[3] Brigham & Womens Hosp, Div Maternal Fetal Med, Dept Obstet & Gynecol, Boston, MA 02115 USA
来源：
OBSTETRICS AND GYNECOLOGY | 2005年 / 106卷 / 05期
关键词：
D O I：
10.1097/01.AOG.0000160481.11517.a0
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
BACKGROUND: Herpes simplex virus (HSV) hepatitis in pregnant women is a rare condition. We report a case confirmed by liver biopsy and successfully treated with empiric intravenous acyclovir. CASE: A 25-year-old primigravida at 34 weeks of gestation presented with fever, thrombocytopenia, and markedly elevated liver enzymes. The patient was treated empirically and was delivered by cesarean. After delivery failed to correct her condition, a liver biopsy revealed HSV hepatitis. The fetus was unaffected and the patient recovered with an extended course of acyclovir. CONCLUSION: Pregnant women are susceptible to disseminated HSV causing hepatitis. A high index of suspicion is necessary to diagnose HSV hepatitis and begin appropriate treatment with acyclovir. Herpes simplex virus hepatitis should be included in the differential diagnosis for liver failure during pregnancy.
引用
收藏
页码：1187 / 1189
页数：3
相关论文
共 50 条
  • [1] Acute Herpes Simplex Virus Hepatitis in Pregnancy
    Carbillon, Lionel
    Bernuau, Jacques
    OBSTETRICS AND GYNECOLOGY, 2020, 136 (01): : 193 - 194
  • [2] Acute Herpes Simplex Virus Hepatitis in Pregnancy
    Calix, Roberto X.
    Loeliger, Kelsey B.
    Burn, Martina S.
    Campbell, Katherine H.
    OBSTETRICS AND GYNECOLOGY, 2020, 135 (02): : 396 - 400
  • [3] Acute Herpes Simplex Virus Hepatitis in Pregnancy Reply
    Calix, Roberto X.
    Campbell, Katherine H.
    OBSTETRICS AND GYNECOLOGY, 2020, 136 (01): : 194 - 194
  • [4] DISSEMINATED HERPES SIMPLEX VIRUS PRESENTING INSIDIOUSLY AS ACUTE HEPATITIS IN PREGNANCY
    Chopra, Maneera
    Reddy, Preethi
    Everett, Jamie
    HEPATOLOGY, 2021, 74 : 419A - 419A
  • [5] Disseminated Herpes Simplex Virus Presenting Insidiously as Acute Hepatitis in Pregnancy
    Chopra, Maneera
    Reddy, Preethi
    Everett, Jamie
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2021, 116 : S1172 - S1172
  • [6] DISSEMINATED HERPES SIMPLEX VIRUS CAUSING ACUTE LIVER FAILURE IN AN IMMUNOCOMPETENT PATIENT
    Moyo, Josephine
    Bilal, Muhammad
    Reed, Mary Jane
    CHEST, 2024, 166 (04) : 2950A - 2951A
  • [7] A literature review of herpes simplex virus hepatitis in pregnancy
    Magawa, Shoichi
    Tanaka, Hiroaki
    Furuhashi, Fumi
    Maki, Shintaro
    Nii, Masafumi
    Toriyabe, Kuniaki
    Ikeda, Tomoaki
    JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2020, 33 (10): : 1774 - 1779
  • [8] A unique presentation of acute liver failure from herpes simplex virus hepatitis
    Gutierrez, C.
    Kebriaei, P.
    Turner, K. A.
    Yemelyanova, A.
    Ariza-Heredia, E. J.
    Foo, W. C.
    TRANSPLANT INFECTIOUS DISEASE, 2016, 18 (04) : 592 - 594
  • [9] Herpes Simplex Virus Hepatitis Causing Fulminant Liver Failure in a Non-Pregnant Woman
    Suresh, Suraj
    Jou, Jessica
    Brown, Kimberly
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2021, 116 : S1181 - S1182
  • [10] Herpes simplex virus in acute liver failure
    Levitsky, Josh
    Thadareddy, Anupama
    Ison, Michael
    Whitley, Richard
    Luby, James
    Friedman, Daniel A.
    Polson, Julie
    Lee, William M.
    Blei, Andres T.
    Lakeman, Fred
    GASTROENTEROLOGY, 2007, 132 (04) : A752 - A752
12345