Current management of lupus nephritis

被引：45

作者：

Houssiau, Frederic A. ^{[1
]}

Lauwerys, Bernard R. ^{[1
]}

机构：

[1] Catholic Univ Louvain, Inst Rech Expt & Clin, Clin Univ St Luc, Pole & Serv Rhumatol, B-1200 Brussels, Belgium

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2013年 / 27卷 / 03期

关键词：

Lupus nephritis; Treatment; Immunosuppression; Optimal care; STAGE RENAL-DISEASE; TERM-FOLLOW-UP; MYCOPHENOLATE-MOFETIL; CONTROLLED-TRIAL; INTRAVENOUS CYCLOPHOSPHAMIDE; DOUBLE-BLIND; IMMUNOSUPPRESSIVE THERAPY; INDUCTION THERAPY; ORAL STEROIDS; ERYTHEMATOSUS;

D O I：

10.1016/j.berh.2013.07.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Despite decades of clinical research aimed at finding the most appropriate immunosuppressive regime, lupus nephritis (LN) remains one of the major disease manifestations of systemic lupus erythematosus (SLE) with a great impact on survival and quality of life. We start this review by defining the disease burden, the real-world challenges and the poor prognostic factors. We then discuss the current anti-inflammatory, cytotoxic and biologic therapies, with special emphasis on the need for optimal global care. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：319 / 328

页数：10

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