Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

被引:36
作者
Bulanov, S. S. [1 ]
Esarey, E. [2 ]
Schroeder, C. B. [2 ]
Leemans, W. P. [1 ,2 ]
Bulanov, S. V. [3 ,4 ,5 ]
Margarone, D. [6 ]
Korn, G. [6 ]
Haberer, T. [7 ]
机构
[1] Univ Calif Berkeley, Berkeley, CA 94720 USA
[2] Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA
[3] Japan Atom Energy Agcy, Kansai Photon Sci Inst, Kizu, Kyoto 6190215, Japan
[4] Russian Acad Sci, Prokhorov Inst Gen Phys, Moscow 119991, Russia
[5] Moscow Inst Phys & Technol, Dolgoprudnyi 141700, Moscow Region, Russia
[6] ASCR, Inst Phys, ELI Beamlines Project, Vvi,FZU, Prague 18221, Czech Republic
[7] Heidelberger Ionenstrahl Therapie Cent HIT, D-69120 Heidelberg, Germany
关键词
ION ACCELERATORS; TUMOR-THERAPY; PROTON; BEAMS; PLASMAS; SYSTEM;
D O I
10.1103/PhysRevSTAB.18.061302
中图分类号
O57 [原子核物理学、高能物理学];
学科分类号
070202 ;
摘要
The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He-3 ions, having almost the same penetration depth as He-4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.
引用
收藏
页数:6
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