An example of regioselective Fischer indole annulation

被引：17

作者：

Christoffers, J ^{[1
]}

机构：

[1] Univ Stuttgart, Inst Organ Chem, D-70569 Stuttgart, Germany

来源：

SYNLETT | 2006年 / 02期

关键词：

carbazole derivatives; indole derivatives; heterocycles; regioselectivity; annulation;

D O I：

10.1055/s-2005-923605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bicyclo[n.4.0]alkan-3-ones (n = 3, 4, 5) with a trans bridge-head configuration give linear annulated tetrahydrocarbazole derivatives in Fischer indole synthesis. The structure of two tetrahydrocarbazoles was confirmed by X-ray crystal analysis. The hexahydroindanone derivative with a cis bridge-head configuration gives, contrastingly, the angular annulation product under the same reaction conditions.

引用

页码：318 / 320

页数：3

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