Effects of a Low-Cost LED Photobiomodulation Therapy Equipment on the Tissue Repair Process

Wound is the interruption of tissue continuity, caused by physical, chemical, mechanical trauma or triggered by a clinical condition, which triggers the fronts of organic defense. The body reacts to the installation of the wounds by initiating the healing process, however, these events may fail due comorbidities may be impair the healing response, resulting in a chronic wound. LED, light-emitting diode, have been successfully used as adjunctive therapies for stimulating skin wound healing however, the parameters used in low-cost equipment have not yet been studied yet. This study aims to evaluate the efficiency of a red LED light therapy equipment on wound healing in rats. The project was approved at CEUA/UESPI under protocol 0298/2019. Two experimental groups were delimited, one treated with LED and one control group. The animals were anesthetized and an area of 2 cm(2) was cut with a skin punch. The treatment was performed for a period of 14 days, in which the regression of the wound was evaluated using the Image J program. When comparing the 14-day regression percentage between the LED treated group and the untreated group, it was observed that there was a significant difference in the regression percentage, being p < 0.05, in which the group treated with LED presented a higher regression percentage than the untreated. LED photobiomodulation therapy has been widely used demonstrating success in the regeneration of lesions by promoting photobiological effects that stimulate this process. This study showed that the low-cost red LED light therapy equipment resulted in faster healing process of the wounds, favoring the reepithelization and recovery of skin integrity.