Recent advances in the synthesis and application of copper nanomaterials based on various DNA scaffolds

被引：51

作者：

Cao, Qiao ^{[1
,2
]}

Li, Jing ^{[1
,2
]}

Wang, Erkang ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

BIOSENSORS & BIOELECTRONICS | 2019年 / 132卷

基金：

中国国家自然科学基金;

关键词：

Copper nanomaterials; DNA; Fluorescence; Biosensing; Logical operation; LABEL-FREE DETECTION; DSDNA-TEMPLATED FORMATION; FLUORESCENT SILVER NANOCLUSTERS; IN-SITU FORMATION; SYBR GREEN I; SENSITIVE DETECTION; ELECTROCHEMICAL DETECTION; ENZYMATIC POLYMERIZATION; ENHANCED FLUORESCENCE; SELECTIVE FORMATION;

D O I：

10.1016/j.bios.2019.01.046

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Fluorescent copper nanomaterials (CuNMs), including copper nanoparticles (CuNPs) and copper nanoclusters (CuNCs), become more and more popular with the abundant raw materials and low cost. A wide range of applications has been explored due to their fascinating properties such as low toxicity, remarkable water solubility, facile synthesis, large Stokes shifts, and good biocompatibility. As a kind of genetic material, DNA exhibits its molecular recognition function and diversity. The marriage between CuNMs and DNA endows DNAtemplated CuNMs (DNA-CuNMs) with unique properties such as fluorescence, electrochemiluminescence and catalytic features. In this review, we summarize the synthesis and recent applications of DNA-CuNMs. Fluorescent CuNMs can be grown on various DNA scaffolds with special sequence design. T base plays an important role in the formation of CuNMs on DNA templates. These fluorescent DNA-CuNMs hold great prospect in logic gate construction, staining and biosensing of DNAs and RNAs, ions, proteins and enzymes, small molecules and so on.

引用

页码：333 / 342

页数：10

共 114 条

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