Fast responsive fluorescence turn-on sensor for Cu2+ and its application in live cell imaging

被引：37

作者：

Wang, Jiaoliang ^{[1
]}

Li, Hao ^{[1
]}

Long, Liping ^{[1
]}

Xiao, Guqing ^{[1
]}

Xie, Dan ^{[1
]}

机构：

[1] Hunan City Univ, Coll Chem & Environm Engn, Yiyang 413000, Peoples R China

来源：

JOURNAL OF LUMINESCENCE | 2012年 / 132卷 / 09期

关键词：

Fluorescence; Copper(II); Hydrolysis; Image; LIVING CELLS; AQUEOUS-SOLUTION; CHEMODOSIMETER; COPPER; CU(II); PRION; CHEMOSENSOR; DERIVATIVES; SELECTIVITY; DISEASES;

D O I：

10.1016/j.jlumin.2012.04.038

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A new effective fluorescent sensor based on rhodamine was synthesized, which was induced by Cu2+ in aqueous media to produce turn-on fluorescence. The new sensor 1 exhibited good selectivity for Cu2+ over other heavy and transition metal (HIM) ions in H2O/CH3CN(7:3, v/v). Upon addition of Cu2+, a remarkable color change from colorless to pink was easily observed by the naked eye, and the dramatic fluorescence turn-on was corroborated. Furthermore, kinetic assay indicates that sensor 1 could be used for real-time tracking of Cu2+ in cells and organisms. In addition, the turn-on fluorescent change upon the addition of Cu2+ was also applied in bioimaging. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：2456 / 2461

页数：6

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