Chitosan based biocomposite scaffolds for bone tissue engineering

被引：280
作者：
Saravanan, S. [1 ]
Leena, R. S. [1 ]
Selvamurugan, N. [1 ]
机构：
[1] SRM Univ, Sch Bioengn, Dept Biotechnol, Kattankulathur 603203, Tamil Nadu, India
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2016年 / 93卷
关键词：
Chitosan; Scaffold; Protein adsorption; Biodegradability; Bone tissue engineering; STEM-CELL PROLIFERATION; DONOR SITE MORBIDITY; IN-VITRO DEGRADATION; COMPOSITE SCAFFOLDS; CONTROLLED-RELEASE; GELATIN SCAFFOLDS; APPLICATIONS FABRICATION; MECHANICAL-PROPERTIES; OSTEOBLAST ADHESION; GLASS NANOPARTICLES;
D O I：
10.1016/j.ijbiomac.2016.01.112
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The clinical demand for scaffolds and the diversity of available polymers provide freedom in the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE). Chitosan (CS) has drawn much of the attention in recent years for its use as graft material either as alone or in a combination with other materials in BTE. The scaffolds should possess a number of properties like porosity, biocompatibility, water retention, protein adsorption, mechanical strength biomineralization and biodegradability suited for BTE applications. In this review, CS and its properties, and the role of CS along with other polymeric and ceramic materials as scaffolds for bone tissue repair applications are highlighted. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：1354 / 1365
页数：12
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