Chitosan based biocomposite scaffolds for bone tissue engineering

被引：280

作者：

Saravanan, S. ^{[1
]}

Leena, R. S. ^{[1
]}

Selvamurugan, N. ^{[1
]}

机构：

[1] SRM Univ, Sch Bioengn, Dept Biotechnol, Kattankulathur 603203, Tamil Nadu, India

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2016年 / 93卷

关键词：

Chitosan; Scaffold; Protein adsorption; Biodegradability; Bone tissue engineering; STEM-CELL PROLIFERATION; DONOR SITE MORBIDITY; IN-VITRO DEGRADATION; COMPOSITE SCAFFOLDS; CONTROLLED-RELEASE; GELATIN SCAFFOLDS; APPLICATIONS FABRICATION; MECHANICAL-PROPERTIES; OSTEOBLAST ADHESION; GLASS NANOPARTICLES;

D O I：

10.1016/j.ijbiomac.2016.01.112

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The clinical demand for scaffolds and the diversity of available polymers provide freedom in the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE). Chitosan (CS) has drawn much of the attention in recent years for its use as graft material either as alone or in a combination with other materials in BTE. The scaffolds should possess a number of properties like porosity, biocompatibility, water retention, protein adsorption, mechanical strength biomineralization and biodegradability suited for BTE applications. In this review, CS and its properties, and the role of CS along with other polymeric and ceramic materials as scaffolds for bone tissue repair applications are highlighted. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：1354 / 1365

页数：12

共 177 条

[1] Biocompatibility of chitosan/Mimosa tenuiflora scaffolds for tissue engineering [J].

Adriana Martel-Estrada, Santos ;

Rodriguez-Espinoza, Brenda ;

Santos-Rodriguez, Eli ;

Jimenez-Vega, Florinda ;

Garcia-Casillas, Perla E. ;

Martinez-Perez, Carlos A. ;

Olivas Armendariz, Imelda .

JOURNAL OF ALLOYS AND COMPOUNDS, 2015, 643 :S119-S123

[2] Effect of size of bioactive glass nanoparticles on mesenchymal stem cell proliferation for dental and orthopedic applications [J].

Ajita, J. ;

Saravanan, S. ;

Selvamurugan, N. .

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2015, 53 :142-149

[3] Chitosan-based delivery systems for protein therapeutics and antigens [J].

Amidi, Maryam ;

Mastrobattista, Enrico ;

Jiskoot, Wim ;

Hennink, Wim E. .

ADVANCED DRUG DELIVERY REVIEWS, 2010, 62 (01) :59-82

[4]

ANDERSON AB, 1987, ACS SYM SER, V343, P306

[5]

Aranaz I., 2009, CURRENT CHEM BIOL, V3, P203, DOI 10.2174/2212796810903020203

[6] Complications of iliac crest bone graft harvesting [J].

Arrington, ED ;

Smith, WJ ;

Chambers, HG ;

Bucknell, AL ;

Davino, NA .

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 1996, (329) :300-309

[7]

Azevedo HS, 2005, BIODEGRADABLE SYSTEMS IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE, P177

[8] Host response to tissue engineered devices [J].

Babensee, JE ;

Anderson, JM ;

McIntire, LV ;

Mikos, AG .

ADVANCED DRUG DELIVERY REVIEWS, 1998, 33 (1-2) :111-139

[9] CONDITIONING SURFACES TO SUIT THE BIOMEDICAL ENVIRONMENT - RECENT PROGRESS [J].

BAIER, RE .

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1982, 104 (04) :257-271

[10] From Natural Bone Grafts to Tissue Engineering Therapeutics: Brainstorming on Pharmaceutical Formulative Requirements and Challenges [J].

Baroli, Biancamaria .

JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 98 (04) :1317-1375

← 1 2 3 4 5 6 7 8 9 10 →