Continued Transmission of HIV Among Young Adults Who Inject Drugs in San Francisco: Still Room for Improvement

被引：9

作者：

Mirzazadeh, Ali ^{[1
]}

Evans, Jennifer L. ^{[1
]}

Hahn, Judith A. ^{[1
,2
]}

Jain, Jennifer ^{[3
]}

Briceno, Alya ^{[1
]}

Shiboski, Stephen ^{[4
]}

Lum, Paula J. ^{[2
]}

Bentsen, Christopher ^{[5
]}

Davis, Geoff ^{[5
]}

Shriver, Kathy ^{[5
]}

Dimapasoc, Melanie ^{[6
]}

Stone, Mars ^{[6
]}

Busch, Michael P. ^{[6
,7
]}

Page, Kimberly ^{[8
]}

机构：

[1] Univ Calif San Francisco, Inst Global Hlth Sci, Dept Epidemiol & Biostat, 550 16th St, San Francisco, CA 94158 USA

[2] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, San Francisco, CA USA

[3] Univ Calif San Diego, Sch Med, Dept Global Publ Hlth & Infect Dis, San Diego, CA 92103 USA

[4] Univ Calif San Francisco, Dept Med, Div HIV Infect Dis & Global Med, 995 Potrero Ave,Bldg 80,Ward 84, San Francisco, CA 94110 USA

[5] Biorad Labs, Redmond, WA USA

[6] Blood Syst Res Inst, San Francisco, CA USA

[7] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 USA

[8] Univ New Mexico, Hlth Sci Ctr, Dept Internal Med, Epidemiol Biostat & Prevent Med, Albuquerque, NM 87131 USA

来源：

AIDS AND BEHAVIOR | 2018年 / 22卷 / 04期

基金：

美国国家卫生研究院;

关键词：

HIV; Incidence; Epidemiology; Drug users; Injection; Young adults; Cohort studies; San Francisco; C VIRUS-INFECTION; NEW-YORK-CITY; HUMAN-IMMUNODEFICIENCY-VIRUS; UNITED-STATES; RACIAL/ETHNIC-DISPARITIES; SEXUAL ORIENTATION; EMERGING EPIDEMIC; RISK BEHAVIORS; HCV INFECTION; BLACK-MEN;

D O I：

10.1007/s10461-017-1988-y

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We measured HIV incidence rate, trend and risk factors in 564 HIV-negative young people (< 30 years) who inject drugs (PWID) in San Francisco between 2000 and 2014. HIV incidence was 0.93/100 person-years (PY; 95% CI 0.50, 1.73). Incidence varied between 0.62/100 PY in 2000-2002 and 1.06/100 PY in 2012-2014 (P for trend = 1.0). HIV incidence varied significantly (P < 0.01) by race/ethnicity: among Hispanics it was 8.19/100 PY (95% CI 3.41, 19.68), African-Americans 4.59/100 PY (95% CI 1.15, 18.37), and Whites 0.26/100 PY (95% CI 0.06, 1.03). Male participants who reported sex with men (MSM) had higher HIV incidence (2.63/100 PY; 95% CI 1.31, 5.25) compared to males who did not report MSM (0.50/100 PY; 95% CI 0.12, 1.99) (P = 0.01). Despite an overall stable HIV incidence trend, incidence was elevated among African-American and Hispanic PWID, and men who have sex with men. Addressing prevention needs in these key populations is critical for the goal of eliminating HIV transmission.

引用

页码：1383 / 1394

页数：12

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