The mitotic origin of chromosomal instability

被引：96

作者：

Bakhoum, Samuel F. ^{[1
,2
,3
]}

Silkworth, William T. ^{[4
,5
]}

Nardi, Isaac K. ^{[4
,6
]}

Nicholson, Joshua M. ^{[4
]}

Compton, Duane A. ^{[1
,2
]}

Cimini, Daniela ^{[4
,7
]}

机构：

[1] Geisel Sch Med Dartmouth, Dept Biochem, Hanover, NH 03755 USA

[2] Geisel Sch Med Dartmouth, Norris Cotton Canc Ctr, Hanover, NH 03755 USA

[3] Harvard Univ, Sch Med, Mt Auburn Hosp, Dept Internal Med, Cambridge, MA 02138 USA

[4] Virginia Tech, Dept Biol Sci, Blacksburg, VA 24061 USA

[5] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

[6] Univ Virginia, Sch Med, Dept Biochem & Mol Genet, Charlottesville, VA 22908 USA

[7] Virginia Tech, Virginia Bioinformat Inst, Blacksburg, VA 24061 USA

来源：

CURRENT BIOLOGY | 2014年 / 24卷 / 04期

关键词：

ANEUPLOIDY;

D O I：

10.1016/j.cub.2014.01.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：R148 / R149

页数：2

共 11 条

[1] Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability [J].

Bakhoum, Samuel F. ;

Genovese, Giulio ;

Compton, Duane A. .

CURRENT BIOLOGY, 2009, 19 (22) :1937-1942

[2] Genome stability is ensured by temporal control of kinetochore-microtubule dynamics [J].

Bakhoum, Samuel F. ;

Thompson, Sarah L. ;

Manning, Amity L. ;

Compton, Duane A. .

NATURE CELL BIOLOGY, 2009, 11 (01) :27-U51

[3] Replication stress links structural and numerical cancer chromosomal instability [J].

Burrell, Rebecca A. ;

McClelland, Sarah E. ;

Endesfelder, David ;

Groth, Petra ;

Weller, Marie-Christine ;

Shaikh, Nadeem ;

Domingo, Enric ;

Kanu, Nnennaya ;

Dewhurst, Sally M. ;

Gronroos, Eva ;

Chew, Su Kit ;

Rowan, Andrew J. ;

Schenk, Arne ;

Sheffer, Michal ;

Howell, Michael ;

Kschischo, Maik ;

Behrens, Axel ;

Helleday, Thomas ;

Bartek, Jiri ;

Tomlinson, Ian R. ;

Swanton, Charles .

NATURE, 2013, 494 (7438) :492-496

[4] Mutations of mitotic checkpoint genes in human cancers [J].

Cahill, DP ;

Lengauer, C ;

Yu, J ;

Riggins, GJ ;

Willson, JKV ;

Markowitz, SD ;

Kinzler, KW ;

Vogelstein, B .

NATURE, 1998, 392 (6673) :300-303

[5] Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells [J].

Cimini, D ;

Howell, B ;

Maddox, P ;

Khodjakov, A ;

Degrassi, F ;

Salmon, ED .

JOURNAL OF CELL BIOLOGY, 2001, 153 (03) :517-527

[6]

Ghadimi BM, 2000, GENE CHROMOSOME CANC, V27, P183, DOI 10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO

[7]

2-P

[8] Genetic instability in colorectal cancers [J].

Lengauer, C ;

Kinzler, KW ;

Vogelstein, B .

NATURE, 1997, 386 (6625) :623-627

[9] Transient defects of mitotic spindle geometry and chromosome segregation errors [J].

Silkworth, William T. ;

Cimini, Daniela .

CELL DIVISION, 2012, 7

[10] Examining the link between chromosomal instability and aneuploidy in human cells [J].

Thompson, Sarah L. ;

Compton, Duane A. .

JOURNAL OF CELL BIOLOGY, 2008, 180 (04) :665-672

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