Mutagenicity of water-soluble ZnO nanoparticles in Ames test

被引:37
作者
Yoshida, Rie [1 ]
Kitamura, Daisuke [1 ]
Maenosono, Shinya [1 ]
机构
[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Nomi, Ishikawa 9231292, Japan
关键词
ZnO nanoparticle; Tetramethylammonium hydroxide; Mutagenicity; Toxicity; Ames test; Bacterial reverse mutation test; ZINC-OXIDE; CARCINOGENS; SALMONELLA; STRAINS; CELLS;
D O I
10.2131/jts.34.119
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
A mutagenicity test was conducted oil water-soluble ZnO nanoparticles capped with tetramethylammonium hydroxide in a bacterial reverse mutation assay using Salmonella typhimurium strains TA98, TA 100, TA 1535 and TA 1537, and Escherichia coli strain WP2uvrA, with and without metabolic activation by S9 mix in the preincubation method. Mutagenicity was negative in all strains.
引用
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页码:119 / 122
页数:4
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