Previous cesarean delivery and the risk of ectopic pregnancy

Objective: To determine whether previous cesarean delivery is an independent risk factor for ectopic pregnancy. Methods: We analyzed data collected between October 1988 and August 1990 from a case-control study of ectopic pregnancy among parous, black, non-Hispanic women, 18-44 years old, at a major metropolitan hospital in Georgia. Cases were 138 women with confirmed ectopic pregnancy; controls were 842 women either seeking abortion or delivering an infant. Unconditional logistic regression was used to estimate the relative risk while controlling for the effects of potential confounders selected a priori. Results: Adjusted for age, parity, marital status, history of pelvic inflammatory disease, infertility, douching, and smoking, the odds ratio was 0.6 (95% confidence interval 0.4-1.1), indicating no significant association. Conclusion: We found no evidence of an increased risk of ectopic pregnancy related to previous cesarean delivery.