Treatment of Acute and Recurrent Idiopathic Pericarditis

被引:52
作者
Lilly, Leonard S. [1 ,2 ]
机构
[1] Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
关键词
colchicine; drug therapy; pericarditis; COLCHICINE; MANAGEMENT; DIAGNOSIS; THERAPY; CORTICOSTEROIDS; DISEASE;
D O I
10.1161/CIRCULATIONAHA.111.066365
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Appropriate therapy for acute idiopathic pericarditis is an NSAID for ≈2 weeks, and it is also reasonable to prescribe colchicine for up to 3 months (the duration used in clinical trials), especially to reduce the rate of recurrence. For initially refractory symptoms, the parenteral NSAID ketorolac may be beneficial. For recurrent episodes of pericarditis, treatment with an NSAID plus colchicine is recommended, but for a more prolonged course. During NSAID treatment, concurrent gastric protection therapy should be considered. Only for truly refractory cases should glucocorticoid therapy be used. © 2013 American Heart Association, Inc.
引用
收藏
页码:1723 / 1726
页数:4
相关论文
共 20 条
[1]   Colchicine treatment for recurrent pericarditis - A decade of experience [J].
Adler, Y ;
Finkelstein, Y ;
Guindo, J ;
de la Serna, AR ;
Shoenfeld, Y ;
Bayes-Genis, A ;
Sagie, A ;
de Luna, AB ;
Spodick, DH .
CIRCULATION, 1998, 97 (21) :2183-2185
[2]   Pretreatment with corticosteroids attenuates the efficacy of colchicine in preventing recurrent pericarditis: a multi-centre all-case analysis [J].
Artom, G ;
Koren-Morag, N ;
Spodick, DH ;
Brucato, A ;
Guindo, J ;
Bayes-de-Luna, A ;
Brambilla, G ;
Finkelstein, Y ;
Granel, B ;
Bayes-Genis, A ;
Schwammenthal, E ;
Adler, Y .
EUROPEAN HEART JOURNAL, 2005, 26 (07) :723-727
[3]   RAPID RESOLUTION OF SYMPTOMATIC ACUTE PERICARDITIS WITH KETOROLAC TROMETHAMINE - A PARENTERAL NONSTEROIDAL ANTIINFLAMMATORY AGENT [J].
ARUNASALAM, S ;
SIEGEL, RJ .
AMERICAN HEART JOURNAL, 1993, 125 (05) :1455-1458
[4]  
Brucato A, 2006, CLIN EXP RHEUMATOL, V24, P45
[5]   INDOMETHACIN-INDUCED SCAR THINNING AFTER EXPERIMENTAL MYOCARDIAL-INFARCTION [J].
HAMMERMAN, H ;
KLONER, RA ;
SCHOEN, FJ ;
BROWN, EJ ;
HALE, S ;
BRAUNWALD, E .
CIRCULATION, 1983, 67 (06) :1290-1295
[6]   Colchicine in addition to conventional therapy for acute pericarditis - Results of the colchicine for acute pericarditis (COPE) trial [J].
Imazio, M ;
Bobbio, M ;
Cecchi, E ;
Demarie, D ;
Demichelis, B ;
Pomari, F ;
Moratti, M ;
Gaschino, G ;
Giammaria, M ;
Ghisio, A ;
Belli, R ;
Trinchero, R .
CIRCULATION, 2005, 112 (13) :2012-2016
[7]   Colchicine as first-choice therapy for recurrent pericarditis - Results of the CORE (COlchicine for REcurrent pericarditis) trial [J].
Imazio, M ;
Bobbio, M ;
Cecchi, E ;
Demarie, D ;
Pomari, F ;
Moratti, M ;
Ghisio, A ;
Belli, R ;
Trinchero, R .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (17) :1987-1991
[8]   Recurrent pain without objective evidence of disease in patients with previous idiopathic or viral acute pericarditis [J].
Imazio, M ;
Demichelis, B ;
Parrini, I ;
Cecchi, E ;
Pomari, F ;
Demarie, D ;
Gaschino, G ;
Ghisio, A ;
Belli, R ;
Trinchero, R .
AMERICAN JOURNAL OF CARDIOLOGY, 2004, 94 (07) :973-975
[9]   Day-hospital treatment of acute pericarditis - A management program for outpatient therapy [J].
Imazio, M ;
Demichelis, B ;
Parrini, I ;
Giuggia, M ;
Cecchi, E ;
Gaschino, G ;
Demarie, D ;
Ghisio, A ;
Trinchero, R .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (06) :1042-1046
[10]   Corticosteroids for recurrent pericarditis - High versus low doses: A nonrandomized observation [J].
Imazio, Massimo ;
Brucato, Antonio ;
Cumetti, Davide ;
Brambilla, Giovanni ;
Demichelis, Brunella ;
Ferro, Silvia ;
Maestroni, Silvia ;
Cecchi, Enrico ;
Belli, Riccardo ;
Palmieri, Giancarlo ;
Trinchero, Rita .
CIRCULATION, 2008, 118 (06) :667-671