Silica gel-Mediated Friedel-Crafts Reaction of lndoles with Functionalized Nitroallylic Acetates via an SN1 Process

被引：2
|
作者：
Ho, Ching-Yin [1 ]
Roy, Suparna [1 ]
Chen, Yan-Ming [1 ]
Chen, Kwunmin [1 ]
机构：
[1] Natl Taiwan Normal Univ, Dept Chem, Taipei 116, Taiwan
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2012年 / 59卷 / 08期
关键词：
Friedel-Crafts reaction; Indole; Nitroallylic acetate; Electrophile; S(N)1; CATALYZED ALLYLIC ALKYLATION; NONREARRANGED MONOTERPENOID UNIT; SIMPLE INDOLE ALKALOIDS; IONIC LIQUIDS; ARYL HALIDES; ALCOHOLS; BENZENE; LIGANDS; KETONES;
D O I：
10.1002/jccs.201100643
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An environmentally friendly Friedel-Crafts reaction was demonstrated between indoles and functionalized nitroallylic acetates in the presence of silica gel, providing the corresponding C-3-selective regioisomers in good to high overall chemical yields (70-93%).
引用
收藏
页码：940 / 946
页数：7
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