Understanding of nanogels swelling behavior through a deep insight into their morphology

被引：24
作者：
Pikabea, Aintzane [1 ]
Aguirre, Garbine [1 ]
Miranda, Jose I. [2 ]
Ramos, Jose [1 ]
Forcada, Jacqueline [1 ]
机构：
[1] Univ Basque Country UPV EHU, Dept Appl Chem, Bionanoparticles Grp, POLYMAT,Fac Chem, Donostia San Sebastian 20080, Spain
[2] Univ Basque Country UPV EHU, Joxe Mari Korta Ctr, Nucl Magnet Resonance Facil, Donostia San Sebastian 20080, Spain
来源：
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2015年 / 53卷 / 17期
关键词：
emulsion polymerization; microstructure; nanogels; stimuli-sensitive polymers; swelling; POLY(N-ISOPROPYLACRYLAMIDE) MICROGEL PARTICLES; PEG TETHERED CHAINS; CROSS-LINK DENSITY; PEGYLATED NANOGELS; BIOMEDICAL APPLICATIONS; STATISTICAL-MECHANICS; PHASE-TRANSITION; PH; TEMPERATURE; NANOPARTICLES;
D O I：
10.1002/pola.27653
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
A thorough understanding of the morphology of the environmental sensitive nanogels was indispensable to obtain a deeper insight on their stimuli-responsive behavior. Therefore, in this work the colloidal characterization and the study of the inner morphology were related by using light scattering technique and H-1-nuclear magnetic resonance transverse relaxation measurements combined with the Flory-Rehner theory. Different biocompatible and dual-stimuli-sensitive nanogel particles based on poly(2-diethylaminoethyl) methacrylate were synthesized using three different crosslinkers: two bifunctional and one multifunctional. All the nanogels obtained had a core-shell type heterogeneous morphology, but they presented completely different swelling behaviors due to their different crosslinking points' distribution and polymeric chains' microstructure. (c) 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015, 53, 2017-2025
引用
收藏
页码：2017 / 2025
页数：9
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