Frailty and incident depressive symptoms in a Chinese sample: the Rugao Longevity and Ageing Study

被引：12

作者：

Chu, Xue-Feng ^{[1
]}

Zhang, Na ^{[2
,3
,4
,5
]}

Shi, Guo-Ping ^{[1
]}

Wang, Yong ^{[1
]}

Wang, Zheng-Dong ^{[1
]}

Guo, Jiang-Hong ^{[1
]}

Jiang, Xiao-Yan ^{[6
]}

Jin, Li ^{[2
,3
,4
]}

Wang, Xiao-Feng ^{[2
,3
,4
,5
]}

Zhu, Yin-Sheng ^{[1
]}

机构：

[1] Rugao Peoples Hosp, Rugao, Jiangsu, Peoples R China

[2] Fudan Univ, MOE, Key Lab Contemporary Anthropol, Shanghai, Peoples R China

[3] Fudan Univ, State Key Lab Genet Engn, Shanghai, Peoples R China

[4] Fudan Univ, Inst Biomed Sci, Sch Life Sci, Shanghai, Peoples R China

[5] Fudan Univ, Huashan Hosp, Natl Clin Res Ctr Ageing & Med, Shanghai, Peoples R China

[6] Tongji Univ, Sch Med, Minist Educ China, Key Lab Arrhythmias, Shanghai, Peoples R China

来源：

PSYCHOGERIATRICS | 2020年 / 20卷 / 05期

基金：

中国国家自然科学基金; 国家重点研发计划;

关键词：

depressive symptoms; frailty; elderly population; grip strength; OLDER-ADULTS; SCALE;

D O I：

10.1111/psyg.12565

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Background To explore the cross-sectional and longitudinal associations between frailty and incident depressive symptoms in a Chinese elderly sample. Methods We analysed data of 1264 older Chinese elders aged 70-87 years in the Rugao Longevity and Ageing Study. The frailty phenotype was assessed using the Fried criteria and depression symptoms was measured by the Geriatric Depression Scale. Results At baseline, 10.6% of participants had depressive symptoms and 9.0% had frailty. In cross-sectional analysis, both pre-frailty (odds ratio (OR) = 2.18, 95% CI 1.35-3.51) and frailty (OR = 4.64, 95% CI 2.49-8.66) were associated with depressive symptoms. In longitudinal analyses, frailty (OR = 2.12, 95% CI 1.17-3.83), instead of pre-frailty, was associated with 1.5-year incident depressive symptoms in a full-adjusted model among participants free of baseline depressive symptoms. In the components of frailty, lower grip strength was associated with increased risk of depressive symptoms onset (OR = 1.56, 95% CI 1.06-2.29). Conclusions Frailty and lower grip strength were associated with incident depressive symptoms in a Chinese elderly sample. Interventions designed to prevent depressive symptoms may be useful by utilising physical aspects of the elderly population.

引用

页码：691 / 698

页数：8

共 20 条

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