Interventions to Improve the Physical Function of ICU Survivors A Systematic Review

被引:97
作者
Calvo-Ayala, Enrique [1 ]
Khan, Babar A. [1 ,3 ,4 ]
Farber, Mark O. [1 ]
Ely, E. Wesley [5 ,6 ,7 ]
Boustani, Malaz A. [2 ,3 ,4 ]
机构
[1] Indiana Univ, Sch Med, Dept Med, Div Pulm Allergy Crit Care Occupat & Sleep Med, Indianapolis, IN USA
[2] Indiana Univ, Sch Med, Dept Med, Div Gen Internal Med & Geriatr, Indianapolis, IN USA
[3] Indiana Univ, Ctr Aging Res, Indianapolis, IN 46204 USA
[4] Regenstrief Inst Hlth Care, Indianapolis, IN USA
[5] Vanderbilt Univ, Sch Med, Dept Med, Div Allergy Pulm & Crit Care Med, Nashville, TN 37212 USA
[6] Vanderbilt Univ, Sch Med, Ctr Hlth Serv Res, Nashville, TN 37212 USA
[7] Vet Affairs Tennessee Valley Geriatr Res Educ & C, Nashville, TN USA
关键词
CRITICALLY-ILL PATIENTS; INTENSIVE-CARE-UNIT; QUALITY-OF-LIFE; RANDOMIZED CONTROLLED-TRIAL; CRITICAL ILLNESS; METHODOLOGICAL QUALITY; MOBILIZING PATIENTS; SEARCH STRATEGIES; CARDIAC-SURGERY; CLINICAL-TRIALS;
D O I
10.1378/chest.13-0779
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: ICU admissions are ever increasing across the United States. Following critical illness, physical functioning (PF) may be impaired for up to 5 years. We performed a systematic review of randomized controlled trials evaluating the efficacy of interventions targeting PF among ICU survivors. The objective of this study was to identify effective interventions that improve long-term PF in ICU survivors. Methods: MEDLINE, Excerpta Medica Database (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Physiotherapy Evidence-Based Database (PEDro) were searched between 1990 and 2012. Two reviewers independently evaluated studies for eligibility, critically appraised the included studies, and extracted data into standardized evidence tables. Results: Fourteen studies met the inclusion criteria. Interventions included exercise/physical therapy (PT), parenteral nutrition, nurse-led follow-up, spontaneous awakening trials, absence of sedation during mechanical ventilation, and early tracheotomy. Nine studies failed to demonstrate efficacy on PF of the ICU survivors. However, early physical exercise and PT-based interventions had a positive effect on long-term PF. Conclusions: The only effective intervention to improve long-term PF in critically ill patients is exercise/PT; its benefit may be greater if started earlier. Further research in this area comparing different interventions and timing is needed.
引用
收藏
页码:1469 / 1480
页数:12
相关论文
共 48 条
[1]   Surviving intensive care: a report from the 2002 Brussels Roundtable [J].
Angus, DC ;
Carlet, J .
INTENSIVE CARE MEDICINE, 2003, 29 (03) :368-377
[2]   Healthcare costs and long-term outcomes after acute respiratory distress syndrome: A phase III trial of inhaled nitric oxide [J].
Angus, Derek C. ;
Clermont, Gilles ;
Linde-Zwirble, Walter T. ;
Musthafa, Amjad A. ;
Dremsizov, Tony T. ;
Lidicker, Jeffrey ;
Lave, Judith R. .
CRITICAL CARE MEDICINE, 2006, 34 (12) :2885-2890
[3]  
[Anonymous], 2008, COCHRANE HDB SYSTEMA, DOI DOI 10.1002/9780470712184
[4]   The PEDro scale provides a more comprehensive measure of methodological quality than the Jadad Scale in stroke rehabilitation literature [J].
Bhogal, SK ;
Teasell, RW ;
Foley, NC ;
Speechley, MR .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2005, 58 (07) :668-673
[5]   Early exercise in critically ill patients enhances short-term functional recovery [J].
Burtin, Chris ;
Clerckx, Beatrix ;
Robbeets, Christophe ;
Ferdinande, Patrick ;
Langer, Daniel ;
Troosters, Thierry ;
Hermans, Greet ;
Decramer, Marc ;
Gosselink, Rik .
CRITICAL CARE MEDICINE, 2009, 37 (09) :2499-2505
[6]   Early versus Late Parenteral Nutrition in Critically Ill Adults [J].
Casaer, Michael P. ;
Mesotten, Dieter ;
Hermans, Greet ;
Wouters, Pieter J. ;
Schetz, Miet ;
Meyfroidt, Geert ;
Van Cromphaut, Sophie ;
Ingels, Catherine ;
Meersseman, Philippe ;
Muller, Jan ;
Vlasselaers, Dirk ;
Debaveye, Yves ;
Desmet, Lars ;
Dubois, Jasperina ;
Van Assche, Aime ;
Vanderheyden, Simon ;
Wilmer, Alexander ;
Van den Berghe, Greet .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (06) :506-517
[7]  
Centre for Clinical Practice, 2009, NICE CLIN GUID
[8]   The PRaCTICaL study of nurse led, intensive care follow-up programmes for improving long term outcomes from critical illness: a pragmatic randomised controlled trial [J].
Cuthbertson, B. H. ;
Rattray, J. ;
Campbell, M. K. ;
Gager, M. ;
Roughton, S. ;
Smith, A. ;
Hull, A. ;
Breeman, S. ;
Norrie, J. ;
Jenkinson, D. ;
Hernandez, R. ;
Johnston, M. ;
Wilson, E. ;
Waldmann, C. .
BMJ-BRITISH MEDICAL JOURNAL, 2009, 339 :1016
[9]   Acquired neuromuscular disorders in critically ill patients: a systematic review [J].
De Jonghe, B ;
Cook, D ;
Sharshar, T ;
Lefaucheur, JP ;
Carlet, J ;
Outin, H .
INTENSIVE CARE MEDICINE, 1998, 24 (12) :1242-1250
[10]   The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study [J].
de Morton, Natalie A. .
AUSTRALIAN JOURNAL OF PHYSIOTHERAPY, 2009, 55 (02) :129-133