Low dose synthetic human atrial natriuretic peptide infusion in a patient with mitral stenosis and severe pulmonary hypertension

被引：13

作者：

Maeda, K ^{[1
]}

Tsutamoto, T

Wada, A

Hisanaga, T

Nishimura, T

Yamada, H

Sasaki, Y

Kinoshita, M

机构：

[1] Shiga Univ Med Sci, Dept Internal Med 1, Otsu, Shiga 5202192, Japan

[2] Shiga Univ Med Sci, Dept Anat, Otsu, Shiga 5202192, Japan

来源：

JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1999年 / 63卷 / 10期

关键词：

atrial natriuretic peptide; fibrosis; heart failure; mitral stenosis;

D O I：

10.1253/jcj.63.816

中图分类号：

N09 [自然科学史]; B [哲学、宗教];

学科分类号：

01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;

摘要：

The present report concerns a case of very low plasma levels of atrial natriuretic peptide (ANP) accompanying severe pulmonary hypertension due to mitral stenosis. There was remarkable fibrosis in the atrium and ANP secretion may have been insufficient. Low-dose infusion (0.025 mu g kg(-1) min(-1)) of synthetic human alpha-ANP infusion was very effective in improving the pulmonary hypertension.

引用

页码：816 / 818

页数：3

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