Current evidence supporting a goal of singletons: a review of maternal and perinatal outcomes associated with twin versus singleton pregnancies after in vitro fertilization and intracytoplasmic sperm injection

被引：16

作者：

Eapen, Abey ^{[1
]}

Ryan, Ginny L. ^{[1
]}

Ten Eyck, Patrick ^{[2
]}

Van Voorhis, Bradley J. ^{[1
]}

机构：

[1] Univ Iowa, Dept Obstet & Gynecol, Iowa City, IA 52242 USA

[2] Univ Iowa, Inst Clin & Translat Sci, Iowa City, IA 52242 USA

来源：

FERTILITY AND STERILITY | 2020年 / 114卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Health care costs; infertility; in vitro fertilization; maternal outcomes; multiple gestation pregnancy; perinatal outcomes; twins; ASSISTED REPRODUCTIVE TECHNOLOGY; LATIN-AMERICAN REGISTRY; EUROPEAN REGISTERS; CHILDREN BORN; CONGENITAL-MALFORMATIONS; MULTIPLE BIRTHS; EMBRYO-TRANSFER; UNITED-STATES; ART; CANADA;

D O I：

10.1016/j.fertnstert.2020.08.1423

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

With increasing use of in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) almost 2% of all babies born in the United States each year are now conceived with these technologies, making outcomes of IVF-ICSI extremely important not only to patients and families but to public health. Twin pregnancy rates after IVF-ICSI in the United States have declined since their peak in 2013 but remain at approximately 1 in 10 to 1 in 20 pregnancies. A review of the current international literature on twin versus singleton pregnancy outcomes after IVF-ICSI treatment confirms statistically significantly higher risks to maternal and perinatal health and statistically significantly higher health care costs. The field of infertility care should continue to work to develop practices that lower twin pregnancy rates to an absolute minimum to maximize the safety of these medical treatments. ((C) 2020 by American Society for Reproductive Medicine.)

引用

页码：690 / 714

页数：25

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