The synthesis and characterization of the polyurethanes with antimicrobial properties

In this experimental research, thin polyurethane films containing reactive functional groups (hydroxyl and amino groups) were synthesized. The raw materials used in the synthesis are: a hydroxyl component (Elastoflex W5516/115) and an isocyanate component (semiprepolimer type) based on 4,4'-diphenylmethane-diisocyanate (MDI) or toluene-2,4-diisocyanate (TDI). Two different antibiotics were adsorbed on these films: amikacin and ceftazidime which formed physical bonds with the polyurethane matrix. The films were characterized by SEM, DMA and a culture of Escherichia coli and a counting room was used in order to determine the antimicrobial efficiency.