Topical Nonsteroidal Anti-Inflammatory Drugs for Macular Edema

被引:47
作者
Russo, Andrea [1 ]
Costagliola, Ciro [2 ]
Delcassi, Luisa [1 ]
Parmeggiani, Francesco [3 ]
Romano, Mario R. [4 ]
dell'Omo, Roberto [2 ]
Semeraro, Francesco [1 ]
机构
[1] Univ Brescia, Dept Neurol & Vis Sci, Eye Clin, I-25123 Brescia, Italy
[2] Univ Molise, Dept Hlth Sci, Eye Clin, I-86100 Campobasso, Italy
[3] Univ Ferrara, Dept Ophthalmol, I-44121 Ferrara, Italy
[4] Ist Clin Humanitas, Eye Clin, I-20089 Milan, Italy
关键词
KETOROLAC TROMETHAMINE 0.5-PERCENT; ENDOTHELIAL GROWTH-FACTOR; SELECTIVE CYCLOOXYGENASE-2 INHIBITOR; RANDOMIZED CONTROLLED-TRIAL; INDUCED OCULAR INFLAMMATION; EARLY DIABETIC-RETINOPATHY; FACTOR-H POLYMORPHISM; OPHTHALMIC SOLUTION; CATARACT-SURGERY; CHOROIDAL NEOVASCULARIZATION;
D O I
10.1155/2013/476525
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Nonsteroidal anti-inflammatory drugs (NSAIDs) are nowadays widely used in ophthalmology to reduce eye inflammation, pain, and cystoid macular edema associated with cataract surgery. Recently, new topical NSAIDs have been approved for topical ophthalmic use, allowing for greater drug penetration into the vitreous. Hence, new therapeutic effects can be achieved, such as reduction of exudation secondary to age-related macular degeneration or diabetic maculopathy. We provide an updated review on the clinical use of NSAIDs for retinal diseases, with a focus on the potential future applications.
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页数:11
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