Specific detection of proteins using photonic crystal waveguides

被引：75

作者：

Buswell, S. C. ^{[1
]}

Wright, V. A. ^{[2
]}

Buriak, J. M. ^{[2
]}

Van, V. ^{[1
]}

Evoy, S. ^{[1
]}

机构：

[1] Univ Alberta, Dept Elect & Comp Engn, Edmonton, AB T6G 2V4, Canada

[2] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

OPTICS EXPRESS | 2008年 / 16卷 / 20期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1364/OE.16.015949

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Specific detection of proteins is demonstrated using planar photonic crystal waveguides. Using immobilized biotin as probe, streptavidin was captured, causing the waveguide mode cut-off to red-shift. The device was shown to detect a 2.5 nm streptavidin film with a 0.86 nm cut-off red-shift. An improved photonic crystal waveguide sensor design is also described and shown to have a 40% improved bulk refractive index response. (C) 2008 Optical Society of America

引用

页码：15949 / 15957

页数：9

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