Branched-chain amino acids and atherosclerosis: friends or foes?

被引：13

作者：

Grajeda-Iglesias, Claudia ^{[1
]}

Rom, Oren ^{[2
]}

Aviram, Michael ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Lipid Res Lab, Rappaport Fac Med, Efron 1, IL-31096 Haifa, Israel

[2] Univ Michigan, Med Ctr, Dept Internal Med, Cardiovasc Ctr, Ann Arbor, MI 48109 USA

来源：

CURRENT OPINION IN LIPIDOLOGY | 2018年 / 29卷 / 02期

关键词：

CORONARY-ARTERY-DISEASE; LEUCINE SUPPLEMENTATION; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; LIPID-METABOLISM; MICE; PROFILES; RISK; ASSOCIATION; EVENTS;

D O I：

10.1097/MOL.0000000000000494

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：166 / 169

页数：4

共 23 条

[11] Branched-chain amino acids are associated with cardiometabolic risk profiles found already in lean, overweight and obese young [J].

Mangge, Harald ;

Zelzer, Sieglinde ;

Prueller, Florian ;

Schnedl, Wolfgang J. ;

Weghuber, Daniel ;

Enko, Dietmar ;

Bergsten, Peter ;

Haybaeck, Johannes ;

Meinitzer, Andreas .

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2016, 32 :123-127

[12] Amino acid profile and metabolic syndrome in a male Mediterranean population: A cross-sectional study [J].

Ntzouvani, A. ;

Nomikos, T. ;

Panagiotakos, D. ;

Fragopoulou, E. ;

Pitsavos, C. ;

McCann, A. ;

Ueland, P. M. ;

Antonopoulou, S. .

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2017, 27 (11) :1021-1030

[13] Human gut microbes impact host serum metabolome and insulin sensitivity [J].

Pedersen, Helle Krogh ;

Gudmundsdottir, Valborg ;

Nielsen, Henrik Bjorn ;

Hyotylainen, Tuulia ;

Nielsen, Trine ;

Jensen, Benjamin A. H. ;

Forslund, Kristoffer ;

Hildebrand, Falk ;

Prifti, Edi ;

Falony, Gwen ;

Le Chatelier, Emmanuelle ;

Levenez, Florence ;

Dore, Joel ;

Mattila, Ismo ;

Plichta, Damian R. ;

Poho, Paivi ;

Hellgren, Lars I. ;

Arumugam, Manimozhiyan ;

Sunagawa, Shinichi ;

Vieira-Silva, Sara ;

Jorgensen, Torben ;

Holm, Jacob Bak ;

Trost, Kajetan ;

Kristiansen, Karsten ;

Brix, Susanne ;

Raes, Jeroen ;

Wang, Jun ;

Hansen, Torben ;

Bork, Peer ;

Brunak, Soren ;

Oresic, Matej ;

Ehrlich, S. Dusko ;

Pedersen, Oluf .

NATURE, 2016, 535 (7612) :376-+

[14] Atherogenicity of amino acids in the lipid-laden macrophage model system in vitro and in atherosclerotic mice: a key role for triglyceride metabolism [J].

Rom, Oren ;

Grajeda-Iglesias, Claudia ;

Najjar, Mahmoud ;

Abu-Saleh, Niroz ;

Volkova, Nina ;

Dar, Dalit Esther ;

Hayek, Tony ;

Aviram, Michael .

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2017, 45 :24-38

[15] It is not just lipids: proatherogenic vs. antiatherogenic roles for amino acids in macrophage foam cell formation [J].

Rom, Oren ;

Aviram, Michael .

CURRENT OPINION IN LIPIDOLOGY, 2017, 28 (01) :85-87

[16] Plasma Branched-Chain Amino Acids and Incident Cardiovascular Disease in the PREDIMED Trial [J].

Ruiz-Canela, Miguel ;

Toledo, Estefania ;

Clish, Clary B. ;

Hruby, Adela ;

Liang, Liming ;

Salas-Salvado, Jordi ;

Razquin, Cristina ;

Corella, Dolores ;

Estruch, Ramon ;

Ros, Emilio ;

Fito, Montserrat ;

Gomez-Gracia, Enrique ;

Aros, Fernando ;

Fiol, Miquel ;

Lapetra, Jose ;

Serra-Majem, Lluis ;

Martinez-Gonzalez, Miguel A. ;

Hu, Frank B. .

CLINICAL CHEMISTRY, 2016, 62 (04) :582-592

[17] Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease [J].

Shah, Svati H. ;

Sun, Jie-Lena ;

Stevens, Robert D. ;

Bain, James R. ;

Muehlbauer, Michael J. ;

Pieper, Karen S. ;

Haynes, Carol ;

Hauser, Elizabeth R. ;

Kraus, William E. ;

Granger, Christopher B. ;

Newgard, Christopher B. ;

Califf, Robert M. ;

Newby, L. Kristin .

AMERICAN HEART JOURNAL, 2012, 163 (05) :844-+

[18] Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events [J].

Shah, Svati H. ;

Bain, James R. ;

Muehlbauer, Michael J. ;

Stevens, Robert D. ;

Crosslin, David R. ;

Haynes, Carol ;

Dungan, Jennifer ;

Newby, L. Kristin ;

Hauser, Elizabeth R. ;

Ginsburg, Geoffrey S. ;

Newgard, Christopher B. ;

Kraus, William E. .

CIRCULATION-CARDIOVASCULAR GENETICS, 2010, 3 (02) :207-U233

[19] Catabolic Defect of Branched-Chain Amino Acids Promotes Heart Failure [J].

Sun, Haipeng ;

Olson, Kristine C. ;

Gao, Chen ;

Prosdocimo, Domenick A. ;

Zhou, Meiyi ;

Wang, Zhihua ;

Jeyaraj, Darwin ;

Youn, Ji-Youn ;

Ren, Shuxun ;

Liu, Yunxia ;

Rau, Christoph D. ;

Shah, Svati ;

Ilkayeva, Olga ;

Gui, Wen-Jun ;

William, Noelle S. ;

Wynn, R. Max ;

Newgard, Christopher B. ;

Cai, Hua ;

Xiao, Xinshu ;

Chuang, David T. ;

Schulze, Paul Christian ;

Lynch, Christopher ;

Jain, Mukesh K. ;

Wang, Yibin .

CIRCULATION, 2016, 133 (21) :2038-2049

[20] Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation [J].

Wang, Qin ;

Holmes, Michael V. ;

Smith, George Davey ;

Ala-Korpela, Mika .

DIABETES CARE, 2017, 40 (12) :1779-1786

← 1 2 3 →