Herpes gestationis (Pemphigoid gestationis)

被引:27
作者
Al-Fouzan, AWS
Galadari, I
Oumeish, I
Oumeish, OY
机构
[1] Al Sabah Hosp, Dept Dermatol, Safat 13002, Kuwait
[2] United Arab Emirates Univ, Dept Dermatol, Dubai, U Arab Emirates
[3] King Hussein Med Ctr, Dept Dermatol, Amman 11831, Jordan
[4] Tulane Univ, Sch Med, Dept Dermatol, New Orleans, LA 70112 USA
关键词
D O I
10.1016/j.clindermatol.2005.10.011
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Herpes gestationis, coined by Milton in 1872, or gestational pemphigoid is the most clearly characterized dermatosis of pregnancy. It is a rare vesiculo-bullous eruption that develops during the last trimester or even postpartum and creates severe pruritus. Its etiology is unknown, but it is considered as an autoimmune-mediated dermatosis closely related to the pemphigoid group. Herpes gestationis is associated with a positive 0 deposition along the base of the epidermis in salt-split skin, with increased frequency of HLA-DR3 and also the combination DR3 and DR4. It has a high risk of prematurity and disappears in the postpartum period within weeks or months. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:109 / 112
页数:4
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